DAGchainer: a tool for mining segmental genome duplications and synteny

被引：258

作者：

Haas, BJ ^{[1
]}

Delcher, AL ^{[1
]}

Wortman, JR ^{[1
]}

Salzberg, SL ^{[1
]}

机构：

[1] Inst Genome Res, Rockville, MD 20850 USA

来源：

BIOINFORMATICS | 2004年 / 20卷 / 18期

关键词：

D O I：

10.1093/bioinformatics/bth397

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Given the positions of protein-coding genes along genomic sequence and probability values for protein alignments between genes, DAGchainer identifies chains of gene pairs sharing conserved order between genomic regions, by identifying paths through a directed acyclic graph (DAG). These chains of collinear gene pairs can represent segmentally duplicated regions and genes within a single genome or syntenic regions between related genomes. Automated mining of the Arabidopsis genome for segmental duplications illustrates the use of DAGchainer.

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收藏

页码：3643 / 3646

页数：4

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