Carbon nanotubes as anti-bacterial agents

被引:112
作者
Mocan, Teodora [1 ,2 ]
Matea, Cristian T. [1 ]
Pop, Teodora [3 ]
Mosteanu, Ofelia [3 ]
Buzoianu, Anca Dana [4 ]
Suciu, Soimita [2 ]
Puia, Cosmin [1 ,5 ]
Zdrehus, Claudiu [1 ,5 ]
Iancu, Cornel [1 ,5 ]
Mocan, Lucian [1 ,5 ]
机构
[1] Octavian Fodor Gastroenterol Inst, Dept Nanomed, 19-21 Croitorilor St, Cluj Napoca, Romania
[2] Iuliu Hatieganu Univ Med & Pharm, Dept Physiol, 3-5 Clinicilor St, Cluj Napoca, Romania
[3] Iuliu Hatieganu Univ Med & Pharm, Gastroenterol Dept 3, 19-21 Croitorilor St, Cluj Napoca, Romania
[4] Iuliu Hatieganu Univ Med & Pharm, Dept Clin Pharmacol, 3-5 Clinicilor St, Cluj Napoca, Romania
[5] Iuliu Hatieganu Univ Med & Pharm, Surg Clin 3, 19-21 Croitorilor St, Cluj Napoca, Romania
关键词
Single-walled carbon nanotubes; Multi-walled carbon nanotubes; Antibacterial agents; RESONANCE-INDUCED PHOTOACTIVATION; GOLD NANOPARTICLES; PHOTOTHERMAL THERAPY; E.-COLI; BACTERIAL CYTOTOXICITY; ANTIMICROBIAL ACTIVITY; BIOFILM FORMATION; IN-VITRO; CANCER; DRUG;
D O I
10.1007/s00018-017-2532-y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Multidrug-resistant bacterial infections that have evolved via natural selection have increased alarmingly at a global level. Thus, there is a strong need for the development of novel antibiotics for the treatment of these infections. Functionalized carbon nanotubes through their unique properties hold great promise in the fight against multidrug-resistant bacterial infections. This new family of nanovectors for therapeutic delivery proved to be innovative and efficient for the transport and cellular translocation of therapeutic molecules. The current review examines the latest progress in the antibacterial activity of carbon nanotubes and their composites.
引用
收藏
页码:3467 / 3479
页数:13
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