Daily spirometry in an acute exacerbation of adult cystic fibrosis patients

被引：3

作者：

Stephen, Michael J. ^{[1
]}

Long, Alex ^{[2
]}

Bonsall, Chad ^{[3
]}

Hoag, Jeffrey B. ^{[1
]}

Shah, Smita ^{[4
]}

Bisberg, Dorothy ^{[4
]}

Holsclaw, Douglas ^{[3
]}

Varlotta, Laurie ^{[5
]}

Fiel, Stan ^{[6
]}

Du, Doantrang ^{[7
]}

Zanni, Robert ^{[7
]}

Hadjiliadis, Denis ^{[3
]}

机构：

[1] Drexel Univ, Sch Med, Div Pulm & Crit Care, Philadelphia, PA USA

[2] Drexel Univ, Sch Publ Hlth, Philadelphia, PA USA

[3] Univ Penn, Div Pulm & Crit Care, Philadelphia, PA USA

[4] Pediat Specialty Ctr, St Barnabas Med Ctr, Barnabas Hlth Med Grp, W Orange, NJ USA

[5] St Christophers Hosp Children, Philadelphia, PA USA

[6] Atlantic Hlth Syst, Morristown, NJ USA

[7] Monmouth Med Ctr, Long Branch, NJ USA

来源：

CHRONIC RESPIRATORY DISEASE | 2018年 / 15卷 / 03期

关键词：

Cystic fibrosis; acute exacerbation; home spirometry; CFQ-R; intravenous antibiotics; QUALITY-OF-LIFE; PULMONARY EXACERBATIONS; RESPIRATORY EXACERBATIONS; ANTIBIOTIC-TREATMENT; MORTALITY; OUTCOMES;

D O I：

10.1177/1479972317743756

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

To help answer the question of length of intravenous antibiotics during an acute exacerbation of cystic fibrosis (CF), we had subjects to follow daily home spirometry while on intravenous antibiotics. CF patients, 18 and older, with an acute exacerbation requiring intravenous antibiotics had a daily FEV1. The average time to a 10% increase over their initial sick FEV1 was calculated, as well as the time to a new baseline. A total of 25 subjects completed the study. Ten of the 25 subjects did not have a sustainable 10% increase in FEV1. Of the 15 subjects with a sustainable 10% increase in FEV1, it took 5.2 days (+/- 4.5) after day 1, while a new baseline was achieved on average at 6.6 days (+/- 4.8) after day 1. Given the wide range of time to a 10% improvement and new baseline, it is recommended there should be flexibility in length of intravenous antibiotics in CF, not by a preset number.

引用

页码：258 / 264

页数：7

共 50 条

[21] Timing of Spirometry May Impact Hospital Length of Stay for Cystic Fibrosis Pulmonary Exacerbation
Krivchenia, Katelyn
Tumin, Dmitry
Nemastil, Christopher J.
Tobias, Joseph D.
Hayes, Don, Jr.
LUNG, 2018, 196 (02) : 207 - 211
[22] The Activities of Daily Living after an Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Koyama, Kazuya
Sakamoto, Susumu
Isshiki, Takuma
Shimizu, Hiroshige
Kurosaki, Atsuko
Homma, Sakae
INTERNAL MEDICINE, 2017, 56 (21) : 2837 - 2843
[23] Adult Care in Cystic Fibrosis
Elborn, J. Stuart
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 40 (06) : 857 - 868
[24] High frequency chest wall oscillation (HFCWO) in the treatment of acute pulmonary exacerbation in adult cystic fibrosis (CF) patients
Krasovskij, Stanislav
Amelina, Elena
Usacheva, Maria
Samoylenko, Victor
Krilova, Natalia
EUROPEAN RESPIRATORY JOURNAL, 2013, 42
[25] The Elusive Role of Airway Infection in Cystic Fibrosis Exacerbation
Caverly, Lindsay J.
VanDevanter, Donald R.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2022, 11 : S40 - S45
[26] Respiratory exacerbation in a young adult with cystic fibrosis and tricuspid atresia
Wood, Jamie
Sawyer, Abbey
Mulrennan, Siobhain
Bullock, Andrew
RESPIROLOGY CASE REPORTS, 2018, 6 (05):
[27] Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation
Sanders, Don B.
Bittner, Rachel C. L.
Rosenfeld, Margaret
Hoffman, Lucas R.
Redding, Gregory J.
Goss, Christopher H.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 182 (05) : 627 - 632
[28] Impulse oscillometry and spirometry measurements relative to personal best values at the time of acute exacerbations of cystic fibrosis in adults
Blin, Timothee
Flament, Thomas
Mankikian, Julie
Chambellan, Arnaud
Marchand-Adam, Sylvain
Plantier, Laurent
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, 2021, 41 (01) : 76 - 84
[29] The Feasibility and Validity of Home Spirometry for People with Cystic Fibrosis: Is It Comparable to Spirometry in the Clinic?
Sopiadou, Athina
Gioulvanidou, Maria
Kogias, Christos
Chrysochoou, Elissavet-Anna
Kalaitzopoulou, Ioustini
Hatziagorou, Elpis
CHILDREN-BASEL, 2025, 12 (03):
[30] Extended-Interval Once-Daily Dosing of Aminoglycosides in Adult and Pediatric Patients with Cystic Fibrosis
Prescott, William A., Jr.
Nagel, Jerod L.
PHARMACOTHERAPY, 2010, 30 (01): : 95 - 108

← 1 2 3 4 5 →