Advances in capillary electrochromatography and micro-high performance liquid chromatography monolithic columns for separation science

被引：203
作者：
Legido-Quigley, C
Marlin, ND
Melin, V
Manz, A
Smith, NW [1 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, Ctr Analyt Sci, London SW7 2AY, England
[2] Kings Coll London, Dept Pharm, Microseparat Grp, London WC2R 2LS, England
来源：
ELECTROPHORESIS | 2003年 / 24卷 / 06期
关键词：
capillary electrochromatography; continuous bed; micro-high performance liquid chromatography monolith; review;
D O I：
10.1002/elps.200390136
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Over the last decade, monoliths or continuous beds have emerged as an alternative to traditional packed-bed columns for use in capillary electrochromatography (CEC) and micro-high performance liquid chromatography (mu-HPLC). Monolithic columns can be divided into two categories: silica-based monolithic columns and rigid organic polymer-based monolithic columns resulting from the polymerization of acrylamide, styrene, acrylate or methacrylate monomers. In this paper, the chemistry and most recent applications of these various types of monoliths in both CEC and mu-HPLC are presented.
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收藏
页码：917 / 944
页数：28
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