Midbrain sonography in patients with essential tremor

被引:94
作者
Stockner, Heike [1 ]
Sojer, Martin [1 ]
Seppi, Klaus [1 ]
Mueller, Joerg [1 ]
Wenning, Gregor K. [1 ]
Schmidauer, Christoph [1 ]
Poewe, Werner [1 ]
机构
[1] Med Univ Innsbruck, Dept Neurol, A-6020 Innsbruck, Austria
关键词
transcranial sonography (TCS); essential tremor (ET); Parkinson's disease (PD); substantia nigra (SN); nigral vulnerability;
D O I
10.1002/mds.21344
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Several studies have reported an increased risk to develop Parkinson's disease (PD) in essential tremor (ET) populations. Hyperechogenicity of the substantia nigra (SN) is a common transcranial sonography (TCS) finding in PD and has been suggested as a PD risk-marker in nonparkinsonian subjects. This study compared SN areas of 44 ET patients with 100 controls and 100 PD patients. Sixteen percent of ET patients had SN hyperechogenicity as compared with 3% of controls and 75% of PD patients. These findings might correspond to an increased risk of ET patients to develop PD. Long-term follow-up will show if those with hyperechogenic SN develop PD, while these without will not. (C) 2007 Movement Disorder Society.
引用
收藏
页码:414 / 417
页数:4
相关论文
共 15 条
[1]   ASSESSING TREMOR SEVERITY [J].
BAIN, PG ;
FINDLEY, LJ ;
ATCHISON, P ;
BEHARI, M ;
VIDAILHET, M ;
GRESTY, M ;
ROTHWELL, JC ;
THOMPSON, PD ;
MARSDEN, CD .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1993, 56 (08) :868-873
[2]   Echogenicity of the substantia nigra in Parkinsons disease and its relation to clinical findings [J].
Berg, D ;
Siefker, C ;
Becker, G .
JOURNAL OF NEUROLOGY, 2001, 248 (08) :684-689
[3]   Relationship of substantia nigra echogenicity and motor function in elderly subjects [J].
Berg, D ;
Siefker, C ;
Ruprecht-Dörfler, P ;
Becker, G .
NEUROLOGY, 2001, 56 (01) :13-17
[4]   Vulnerability of the nigrostriatal system as detected by transcranial ultrasound [J].
Berg, D ;
Becker, G ;
Zeiler, B ;
Tucha, O ;
Hofmann, E ;
Preier, M ;
Benz, P ;
Jost, W ;
Reiners, K ;
Lange, KW .
NEUROLOGY, 1999, 53 (05) :1026-1031
[5]   Rest tremor in patients with essential tremor - Prevalence, clinical correlates, and electrophysiologic characteristics [J].
Cohen, O ;
Pullman, S ;
Jurewicz, E ;
Watner, D ;
Louis, ED .
ARCHIVES OF NEUROLOGY, 2003, 60 (03) :405-410
[6]   Consensus statement of the Movement Disorder Society on tremor [J].
Deuschl, G ;
Bain, P ;
Brin, M .
MOVEMENT DISORDERS, 1998, 13 :2-23
[7]   Prevalence of essential tremor - Door-to-door neurologic exams in Mersin Province, Turkey [J].
Dogu, O ;
Sevim, S ;
Camdeviren, H ;
Sasmaz, T ;
Bugdayci, R ;
Aral, M ;
Kaleagasi, H ;
Un, S ;
Louis, ED .
NEUROLOGY, 2003, 61 (12) :1804-1806
[8]   ACCURACY OF CLINICAL-DIAGNOSIS OF IDIOPATHIC PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY OF 100 CASES [J].
HUGHES, AJ ;
DANIEL, SE ;
KILFORD, L ;
LEES, AJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) :181-184
[9]  
Jankovic J, 2000, NEUROLOGY, V54, pS21
[10]   THE RELATIONSHIP OF ESSENTIAL TREMOR TO OTHER MOVEMENT-DISORDERS - REPORT ON 678 PATIENTS [J].
KOLLER, WC ;
BUSENBARK, K ;
MINER, K ;
ADAIR, JC ;
AIGNER, BR ;
ALBIN, RI ;
ALEXANDER, DN ;
ANTO, CM ;
BENDER, SE ;
BERG, MJ ;
BERGIA, BM ;
BLALOCK, E ;
BURNS, RS ;
COUCH, JR ;
CRISOSTOMO, EA ;
DAVIS, LS ;
DAVIS, TL ;
DIETRICH, DW ;
DIMITSOPULOS, TM ;
DOORENBOS, D ;
ELLIS, JR ;
ERTAG, WD ;
FACTOR, SA ;
FEIGIN, AS ;
FREY, KA ;
GADDIS, KA ;
GIBSON, GL ;
GOLDEN, RE ;
GORDON, MF ;
GREENAMYRE, JT ;
GRIFFITH, PA ;
GROTTA, JC ;
HAUSER, RA ;
HEIDEBRINK, JL ;
HIGGINS, DC ;
HILL, SA ;
HILL, TA ;
HUBBLE, JP ;
HUTTON, JT ;
JOHNSTON, W ;
KIEBURTZ, KD ;
KURLAN, RM ;
LABUNETZ, WH ;
LIEBERMAN, AN ;
MAJUMDAR, L ;
MARAGOS, WF ;
MCCLOSKEY, T ;
MCPHERSON, SL ;
MILLER, BR ;
NINO, HE .
ANNALS OF NEUROLOGY, 1994, 35 (06) :717-723