Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]tri-azines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines

被引：13

作者：

Izmest'ev, Alexei N. ^{[1
,2
]}

Vinogradov, Dmitry B. ^{[1
]}

Kolotyrkina, Natalya G. ^{[1
]}

Kravchenko, Angelina N. ^{[1
,3
]}

Gazieva, Galina A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Leninsky Prosp 47, Moscow 119991, Russia

[2] Natl Univ Sci & Technol MISiS, 4 Leninsky Prosp, Moscow 119049, Russia

[3] Plekhanov Russian Univ Econ, 36 Stremyanny Lane, Moscow 117997, Russia

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 17卷

关键词：

amidine rearrangement; cyclocondensation; heterocycles; thiazolidine-4-one; 1; 2; 4-triazine; BIOLOGICAL-ACTIVITY; DERIVATIVES; THIAZOLIDIN-4-ONE;

D O I：

10.3762/bjoc.17.87

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two series of functionalized imidazothiazolotriazine derivatives were synthesized via the condensation of imidazo[4,5-e]-1,2,4-triazine-3-thiones with acetylenedicarboxylic acid dimethyl and diethyl esters (DMAD and DEAD) and subsequent base-catalyzed rearrangement of the obtained imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazines into regioisomeric imidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazine derivatives.

引用

页码：1141 / 1148

页数：8

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