Acetylenes in catalysis: Enantioselective additions to carbonyl groups and imines and applications beyond

被引：290

作者：

Cozzi, PG

Hilgraf, R

Zimmermann, N

机构：

[1] Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

[2] Celgene, San Diego, CA 92121 USA

[3] Vertex Pharmaceut Inc, San Diego, CA 92121 USA

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 2004卷 / 20期

关键词：

acetylenes; enantioselectivity; catalysis; metal complexes;

D O I：

10.1002/ejoc.200400246

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetylenes represent a class of versatile building blocks, which are widely used in organic synthesis. Over the past years, a considerable number of publications have appeared that focus on the enantioselective addition of acetylenes to carbonyls and imines. In addition, novel applications for acetylenes have emerged in the literature. We herein present an overview of recent results in these areas. (C) Wiley-VCH Verlag GmbH Co.

引用

页码：4095 / 4105

页数：11

共 167 条

[1] Stereoselective approach to alk-2-yne-1,4-diols. Application to the synthesis of musclide B [J].