Can the Suppressive Activity of Myeloid-Derived Suppressor Cells Be "Chop"ped?

被引:10
作者
Condamine, Thomas [1 ]
Gabrilovich, Dmitry I. [1 ]
机构
[1] Wistar Inst Anat & Biol, Philadelphia, PA 19104 USA
关键词
STRESS;
D O I
10.1016/j.immuni.2014.08.016
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators of immune responses. In this issue of Immunity, Thevenot et al. (2014) showed that in tumors, the suppressive activity of MDSCs is regulated by transcription factor Chop.
引用
收藏
页码:341 / 342
页数:2
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