Racial and ethnic disparities in assisted reproductive technology outcomes in the United States

被引:150
作者
Fujimoto, Victor Y. [1 ]
Luke, Barbara [2 ,3 ]
Brown, Morton B. [4 ]
Jain, Tarun [5 ]
Armstrong, Alicia [6 ]
Grainger, David A. [7 ,8 ]
Hornstein, Mark D. [9 ]
机构
[1] Univ Calif San Francisco, Ctr Reprod Hlth, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94115 USA
[2] Michigan State Univ, Dept Obstet Gynecol & Reprod Biol, E Lansing, MI 48824 USA
[3] Michigan State Univ, Dept Epidemiol, E Lansing, MI 48824 USA
[4] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA
[5] Univ Illinois, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Chicago, IL 60612 USA
[6] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Reprod & Adult Endocrinol, NIH, Bethesda, MD USA
[7] Univ Kansas, Sch Med, Dept Obstet & Gynecol, Wichita, KS 67214 USA
[8] Univ Kansas, Sch Med, Ctr Reprod Med, Wichita, KS 67214 USA
[9] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Obstet Gynecol & Reprod Biol, Boston, MA 02115 USA
关键词
Ethnic disparities; racial disparities; Asian; black; Hispanic; ART outcomes; IVF outcomes; IVF pregnancy rates; IVF live birth rates; prematurity; growth restriction; IN-VITRO FERTILIZATION; LOW-BIRTH-WEIGHT; ADVERSE PREGNANCY OUTCOMES; INTRAUTERINE GROWTH-CURVES; GLUCOSE-TOLERANCE TEST; BODY-MASS INDEX; PERINATAL OUTCOMES; GESTATIONAL-AGE; AFRICAN-AMERICAN; ASIAN ETHNICITY;
D O I
10.1016/j.fertnstert.2008.10.061
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States. Design: Historical cohort study. Setting: Clinic-based data. Patient(s): A total of 139,027 ART cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System online database for 2004-2006, limited to white, Asian, black, and Hispanic women. Intervention(S): None. Main Outcome Measure(s): Logistic regression was used to model the odds of pregnancy and live birth; among singletons and twins, the odds of preterm birth and fetal growth restriction. Results are presented as adjusted odds ratios, with white women as the reference group. Result(S): The odds of pregnancy were reduced for Asians (0.86), and the odds of live birth were reduced for all 1 groups: Asian (0.90), black (0.62), and Hispanic (0.87) women. Among singletons, moderate and severe growth restriction were increased for all infants in all three minority groups (Asians [1.78, 2.05]; blacks [1.81, 2.17]; Hispanics [1.36, 1.64]), and preterm birth was increased among black (1.79) and Hispanic women (1.22). Among twins, the odds for moderate growth restriction were increased for infants of Asian (1.30) and black women (1.97). and severe growth restriction was increased among black women (3.21). The odds of preterm birth were increased for blacks (1.64) and decreased for Asians (0.70). Conclusion(S): There are significant disparities in ART outcomes according to ethnicity. (Fertil Steril (R) 2010; 93:382-90. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:382 / 390
页数:9
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