Epstein-Barr virus in the pathogenesis of Hodgkin's disease

被引:8
作者
Dolcetti, R [1 ]
Boiocchi, M [1 ]
机构
[1] Ctr Riferimento Oncol, Div Expt Oncol 1, I-33081 Aviano, PN, Italy
关键词
Epstein-Barr virus; Hodgkin's disease; lymphomagenesis;
D O I
10.1016/S0753-3322(97)86237-3
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Epidemiologic and clinico-pathologic features of Hodgkin's disease suggest that an infectious agent may be involved in the pathogenesis of this puzzling disorder. Recently accumulated data provide direct evidence supporting a causal role of Epstein-Barr virus in a significant proportion of cases. In addition to allowing a better understanding of the complex pathogenesis of Hodgkin's disease, these virological advances, briefly reviewed herein, also constitute an important basis for the development of new therapeutic strategies. (C) 1998 Elsevier, Paris.
引用
收藏
页码:13 / 25
页数:13
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