Lutein across the Lifespan: From Childhood Cognitive Performance to the Aging Eye and Brain

被引：68
作者：
Stringham, James M. [1 ]
Johnson, Elizabeth J. [2 ]
Hammond, B. Randy [3 ]
机构：
[1] Duke Eye Ctr, Visual Performance Lab, Durham, NC USA
[2] Tufts Univ, Friedman Sch Nutr, Boston, MA 02111 USA
[3] Univ Georgia, Dept Psychol, Athens, GA 30602 USA
来源：
CURRENT DEVELOPMENTS IN NUTRITION | 2019年 / 3卷 / 07期
关键词：
lutein; zeaxanthin; carotenoids; nutrition; lifespan; eye; brain; vision; cognition; PIGMENT OPTICAL-DENSITY; MACULAR PIGMENT; OXIDATIVE STRESS; CONTRAST SENSITIVITY; VISUAL PERFORMANCE; OLDER-ADULTS; AGE; CAROTENOIDS; ZEAXANTHIN; DEGENERATION;
D O I：
10.1093/cdn/nzz066
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Lutein is a non-provitamin A dietary carotenoid found in dark green leafy vegetables, corn, eggs, and avocados. Among the carotenoids, lutein and its isomer, zeaxanthin, are the only 2 that cross the blood-retina barrier to form macular pigment in the retina. Lutein also preferentially accumulates in the human brain across multiple life stages. A variety of scientific evidence supports a role for lutein in visual as well as cognitive function across the lifespan. The purpose of this review is to summarize the latest science on lutein's role in the eye and the brain across different ages.
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