Merkel Cell Polyomavirus in Cutaneous Swabs

被引：88

作者：

Foulongne, Vincent ^{[1
,2
]}

Kluger, Nicolas ^{[1
]}

Dereure, Olivier ^{[1
]}

Mercier, Gregoire ^{[1
]}

Moles, Jean-Pierre ^{[1
]}

Guillot, Bernard ^{[1
]}

Segondy, Michel ^{[1
]}

机构：

[1] Univ Montpellier 1, Montpellier, France

[2] Montpellier Univ Hosp, Montpellier, France

来源：

EMERGING INFECTIOUS DISEASES | 2010年 / 16卷 / 04期

关键词：

CARCINOMA; MCV; EXPRESSION; INFECTION; TUMORS; DNA;

D O I：

10.3201/eid1604.091278

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To assess the usefulness of using cutaneous swabs to detect Merkel cell polyomavirus (MCPyV) DNA, we analyzed swabs from persons with Merkel cell carcinoma (MCC), others with skin diseases, and healthy volunteers. MCPyV was detected in at least 1 sample from virtually all participants. Viral loads were higher in samples from patients with MCC.

引用

收藏

页码：685 / 687

页数：3

相关论文

共 15 条

[11] Merkel cell carcinoma of the skin: pathological and molecular evidence for a causative role of MCV in oncogenesis [J].

Sastre-Garau, Xavier ;

Peter, Martine ;

Avril, Marie-Francoise ;

Laude, Helene ;

Couturier, Jerome ;

Rozenberg, Flore ;

Almeida, Anna ;

Boitier, Francoise ;

Carlotti, Agnes ;

Couturaud, Benoit ;

Dupin, Nicolas .

JOURNAL OF PATHOLOGY, 2009, 218 (01) :48-56

[12] T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus [J].

Shuda, Masahiro ;

Feng, Huichen ;

Kwun, Hyun Jin ;

Rosen, Steven T. ;

Gjoerup, Ole ;

Moore, Patrick S. ;

Chang, Yuan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (42) :16272-16277

[13] Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors [J].

Shuda, Masahiro ;

Arora, Reety ;

Kwun, Hyun Jin ;

Feng, Huichen ;

Sarid, Ronit ;

Fernandez-Figueras, Maria-Teresa ;

Tolstov, Yanis ;

Gjoerup, Ole ;

Mansukhani, Mahesh M. ;

Swerdlow, Steven H. ;

Chaudhary, Preet M. ;

Kirkwood, John M. ;

Nalesnik, Michael A. ;

Kant, Jeffrey A. ;

Weiss, Lawrence M. ;

Moore, Patrick S. ;

Chang, Yuan .

INTERNATIONAL JOURNAL OF CANCER, 2009, 125 (06) :1243-1249

[14] Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays [J].

Tolstov, Yanis L. ;

Pastrana, Diana V. ;

Feng, Huichen ;

Becker, Juergen C. ;

Jenkins, Frank J. ;

Moschos, Stergios ;

Chang, Yuan ;

Buck, Christopher B. ;

Moore, Patrick S. .

INTERNATIONAL JOURNAL OF CANCER, 2009, 125 (06) :1250-1256

[15] Merkel Cell Polyomavirus DNA in Persons without Merkel Cell Carcinoma [J].

Wieland, Ulrike ;

Mauch, Cornelia ;

Kreuter, Alexander ;

Krieg, Thomas ;

Pfister, Herbert .

EMERGING INFECTIOUS DISEASES, 2009, 15 (09) :1496-1498