Merkel Cell Polyomavirus in Cutaneous Swabs

被引：88

作者：

Foulongne, Vincent ^{[1
,2
]}

Kluger, Nicolas ^{[1
]}

Dereure, Olivier ^{[1
]}

Mercier, Gregoire ^{[1
]}

Moles, Jean-Pierre ^{[1
]}

Guillot, Bernard ^{[1
]}

Segondy, Michel ^{[1
]}

机构：

[1] Univ Montpellier 1, Montpellier, France

[2] Montpellier Univ Hosp, Montpellier, France

来源：

EMERGING INFECTIOUS DISEASES | 2010年 / 16卷 / 04期

关键词：

CARCINOMA; MCV; EXPRESSION; INFECTION; TUMORS; DNA;

D O I：

10.3201/eid1604.091278

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To assess the usefulness of using cutaneous swabs to detect Merkel cell polyomavirus (MCPyV) DNA, we analyzed swabs from persons with Merkel cell carcinoma (MCC), others with skin diseases, and healthy volunteers. MCPyV was detected in at least 1 sample from virtually all participants. Viral loads were higher in samples from patients with MCC.

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收藏

页码：685 / 687

页数：3

相关论文

共 15 条

[1] MC Polyomavirus Is Frequently Present in Merkel Cell Carcinoma of European Patients [J].

Becker, Juergen C. ;

Houben, Roland ;

Ugurel, Selma ;

Trefzer, Uwe ;

Pfoehler, Claudia ;

Schrama, David .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (01) :248-250

[2] Merkel Cell Polyomavirus DNA in Respiratory Specimens from Children and Adults [J].

Bialasiewicz, Seweryn ;

Lambert, Stephen B. ;

Whiley, David M. ;

Nissen, Michael D. ;

Sloots, Theo P. .

EMERGING INFECTIOUS DISEASES, 2009, 15 (03) :492-494

[3] Merkel Cell Polyomavirus Expression in Merkel Cell Carcinomas and Its Absence in Combined Tumors and Pulmonary Neuroendocrine Carcinomas [J].

Busam, Klaus J. ;

Jungbluth, Achim A. ;

Rekthman, Natasha ;

Coit, Daniel ;

Pulitzer, Melissa ;

Bini, Jason ;

Arora, Reety ;

Hanson, Nicole C. ;

Tassello, Jodie A. ;

Frosina, Denise ;

Moore, Patrick ;

Chang, Yuan .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2009, 33 (09) :1378-1385

[4] Merkel Cell Polyomavirus in Cutaneous Squamous Cell Carcinoma of Immunocompetent Individuals [J].

Dworkin, Amy M. ;

Tseng, Stephanie Y. ;

Allain, Dawn C. ;

Iwenofu, O. Hans ;

Peters, Sara B. ;

Toland, Amanda E. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (12) :2868-2874

[5]

Feng HC, 2008, SCIENCE, V319, P1096, DOI 10.1126/science.1152586

[6]

FOULONGNE V, 2009, BR J DERMATOL 0706

[7] Merkel Cell Polyomavirus Is More Frequently Present in North American than Australian Merkel Cell Carcinoma Tumors [J].

Garneski, Kelly M. ;

Warcola, Ashley H. ;

Feng, Qinghua ;

Kiviat, Nancy B. ;

Leonard, J. Helen ;

Nghiem, Paul .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (01) :246-248

[8] Frequent detection of Merkel cell polyomavirus in human Merkel cell carcinomas and identification of a unique deletion in the VP1 gene [J].

Kassem, Ahmad ;

Schoepflin, Anja ;

Diaz, Carlos ;

Weyers, Wolfgang ;

Stickeler, Elmar ;

Werner, Martin ;

zur Hausen, Axel .

CANCER RESEARCH, 2008, 68 (13) :5009-5013

[9] Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients [J].

Kassem, Ahmad ;

Technau, Kristin ;

Kurz, Anna Kordelia ;

Pantulu, Deepa ;

Loening, Marie ;

Kayser, Gian ;

Stickeler, Elmar ;

Weyers, Wolfgang ;

Diaz, Carlos ;

Werner, Martin ;

Nashan, Dorothee ;

zur Hausen, Axel .

INTERNATIONAL JOURNAL OF CANCER, 2009, 125 (02) :356-361

[10]

LOYO M, 2009, INT J CANC 0708