Merkel Cell Polyomavirus in Cutaneous Swabs

被引:87
作者
Foulongne, Vincent [1 ,2 ]
Kluger, Nicolas [1 ]
Dereure, Olivier [1 ]
Mercier, Gregoire [1 ]
Moles, Jean-Pierre [1 ]
Guillot, Bernard [1 ]
Segondy, Michel [1 ]
机构
[1] Univ Montpellier 1, Montpellier, France
[2] Montpellier Univ Hosp, Montpellier, France
关键词
CARCINOMA; MCV; EXPRESSION; INFECTION; TUMORS; DNA;
D O I
10.3201/eid1604.091278
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To assess the usefulness of using cutaneous swabs to detect Merkel cell polyomavirus (MCPyV) DNA, we analyzed swabs from persons with Merkel cell carcinoma (MCC), others with skin diseases, and healthy volunteers. MCPyV was detected in at least 1 sample from virtually all participants. Viral loads were higher in samples from patients with MCC.
引用
收藏
页码:685 / 687
页数:3
相关论文
共 15 条
  • [1] MC Polyomavirus Is Frequently Present in Merkel Cell Carcinoma of European Patients
    Becker, Juergen C.
    Houben, Roland
    Ugurel, Selma
    Trefzer, Uwe
    Pfoehler, Claudia
    Schrama, David
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (01) : 248 - 250
  • [2] Merkel Cell Polyomavirus DNA in Respiratory Specimens from Children and Adults
    Bialasiewicz, Seweryn
    Lambert, Stephen B.
    Whiley, David M.
    Nissen, Michael D.
    Sloots, Theo P.
    [J]. EMERGING INFECTIOUS DISEASES, 2009, 15 (03) : 492 - 494
  • [3] Merkel Cell Polyomavirus Expression in Merkel Cell Carcinomas and Its Absence in Combined Tumors and Pulmonary Neuroendocrine Carcinomas
    Busam, Klaus J.
    Jungbluth, Achim A.
    Rekthman, Natasha
    Coit, Daniel
    Pulitzer, Melissa
    Bini, Jason
    Arora, Reety
    Hanson, Nicole C.
    Tassello, Jodie A.
    Frosina, Denise
    Moore, Patrick
    Chang, Yuan
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2009, 33 (09) : 1378 - 1385
  • [4] Merkel Cell Polyomavirus in Cutaneous Squamous Cell Carcinoma of Immunocompetent Individuals
    Dworkin, Amy M.
    Tseng, Stephanie Y.
    Allain, Dawn C.
    Iwenofu, O. Hans
    Peters, Sara B.
    Toland, Amanda E.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (12) : 2868 - 2874
  • [5] Feng HC, 2008, SCIENCE, V319, P1096, DOI 10.1126/science.1152586
  • [6] FOULONGNE V, 2009, BR J DERMATOL 0706
  • [7] Merkel Cell Polyomavirus Is More Frequently Present in North American than Australian Merkel Cell Carcinoma Tumors
    Garneski, Kelly M.
    Warcola, Ashley H.
    Feng, Qinghua
    Kiviat, Nancy B.
    Leonard, J. Helen
    Nghiem, Paul
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (01) : 246 - 248
  • [8] Frequent detection of Merkel cell polyomavirus in human Merkel cell carcinomas and identification of a unique deletion in the VP1 gene
    Kassem, Ahmad
    Schoepflin, Anja
    Diaz, Carlos
    Weyers, Wolfgang
    Stickeler, Elmar
    Werner, Martin
    zur Hausen, Axel
    [J]. CANCER RESEARCH, 2008, 68 (13) : 5009 - 5013
  • [9] Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients
    Kassem, Ahmad
    Technau, Kristin
    Kurz, Anna Kordelia
    Pantulu, Deepa
    Loening, Marie
    Kayser, Gian
    Stickeler, Elmar
    Weyers, Wolfgang
    Diaz, Carlos
    Werner, Martin
    Nashan, Dorothee
    zur Hausen, Axel
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2009, 125 (02) : 356 - 361
  • [10] LOYO M, 2009, INT J CANC 0708