Structural and dynamic properties of four-way helical junctions in DNA molecules

被引：0
|
作者：
Lilley, DMJ [1 ]
机构：
[1] Univ Dundee, Dept Biochem, Canc Res UK Nucle Acid Struct Res Grp, Dundee DD1 5EH, Scotland
来源：
NUCLEIC ACIDS: CURVATURE AND DEFORMATION: RECENT ADVANCES AND NEW PARADIGMS | 2004年 / 884卷
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D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Four-way helical junctions in DNA are the central intermediates in genetic recombination. In the presence of divalent metal ions they fold into the stacked X-structure by the pairwise coaxial stacking of helical arms. Exchange between alternative stacking conformers occurs in solution. The structure of four-way junctions is specifically recognised by proteins, notably by the resolving enzymes.
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页码：145 / 164
页数：20
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