Treatment of recurrent conjunctival epithelial neoplasia with topical mitomycin C

被引：66
|
作者：
Heigle, TJ [1 ]
Stulting, RD [1 ]
Palay, DA [1 ]
机构：
[1] EMORY UNIV,DEPT OPHTHALMOL,ATLANTA,GA 30322
来源：
AMERICAN JOURNAL OF OPHTHALMOLOGY | 1997年 / 124卷 / 03期
关键词：
D O I：
10.1016/S0002-9394(14)70834-7
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
PURPOSE: To study the effect of topical mitomycin C on conjunctival squamous neoplasia. METHODS: Three patients with recurrent conjunctival epithelial neoplasia were treated with topical mitomycin C 0.04-%. RESULTS: Six to 9 months after treatment, no patient had clinical evidence of tumor recurrence. Conjunctival biopsy in two patients and cytology in one patient showed no evidence of tumor 1 to 4 months after treatment. One patient required short-term treatment for corneal edema and epithelial toxicity. CONCLUSION: Topical mitomycin C caused tumor regression without recurrence for 6 to 9 months after treatment.
引用
收藏
页码：397 / 399
页数：3
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