Disorders of lipids in chronic kidney disease: present and future. A review

被引：0

作者：

Chelioti, E. ^{[1
]}

Christofilidis, G. ^{[1
]}

Theodoropoulou, E. ^{[1
]}

机构：

[1] Tzaneio Gen Hosp Piraeus, Dept Nephrol, Piraeus, Greece

来源：

SCIENTIFIC CHRONICLES | 2022年 / 27卷 / 01期

关键词：

chronic kidney disease; dyslipidemia; oxidative stress and inflammation; LOW-DENSITY-LIPOPROTEIN; NEPHROTIC SYNDROME MECHANISMS; STAGE RENAL-DISEASE; OXIDATIVE STRESS; CHOLESTEROL-METABOLISM; CARDIOVASCULAR EVENTS; MOLECULAR-MECHANISMS; DYSLIPIDEMIA; ABNORMALITIES; PCSK9;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic kidney disease (CKD) is associated with dyslipidemia that includes high triglycerides, low HDL-cholesterol, and modified lipoprotein synthesis. Cardiovascular disease is the leading cause of death in CKD, especially in patients with end-stage renal disease. Therefore, treatments to reduce cardiovascular risk are urgently needed in CKD. Therapeutic strategies in this patient population aim at controlling modifiable cardiovascular risk factors, including dyslipidemia. The aim of the present review is the effect of renal impairment, oxidative stress and inflammation on the lipid profile of patients with CKD.

引用

页码：93 / 106

页数：14

共 47 条

[1]

Agrawal S, 2018, NAT REV NEPHROL, V14, P57, DOI 10.1038/nrneph.2017.155

[2]

[Anonymous], 2018, NEPHROL DIAL TRANSPL

[3] Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 [J].

Bikbov, Boris ;

Purcell, Carrie ;

Levey, Andrew S. ;

Smith, Mari ;

Abdoli, Amir ;

Abebe, Molla ;

Adebayo, Oladimeji M. ;

Afarideh, Mohsen ;

Agarwal, Sanjay Kumar ;

Agudelo-Botero, Marcela ;

Ahmadian, Elham ;

Al-Aly, Ziyad ;

Alipour, Vahid ;

Almasi-Hashiani, Amir ;

Al-Raddadi, Rajaa M. ;

Alvis-Guzman, Nelson ;

Amini, Saeed ;

Andrei, Tudorel ;

Andrei, Catalina Liliana ;

Andualem, Zewudu ;

Anjomshoa, Mina ;

Arabloo, Jalal ;

Ashagre, Alebachew Fasil ;

Asmelash, Daniel ;

Ataro, Zerihun ;

Atout, Maha Moh'd Wahbi ;

Ayanore, Martin Amogre ;

Badawi, Alaa ;

Bakhtiari, Ahad ;

Ballew, Shoshana H. ;

Balouchi, Abbas ;

Banach, Maciej ;

Barquera, Simon ;

Basu, Sanjay ;

Bayih, Mulat Tirfie ;

Bedi, Neeraj ;

Bello, Aminu K. ;

Bensenor, Isabela M. ;

Bijani, Ali ;

Boloor, Archith ;

Borzi, Antonio M. ;

Camera, Luis Alberto ;

Carrero, Juan J. ;

Carvalho, Felix ;

Castro, Franz ;

Catala-Lopez, Ferran ;

Chang, Alex R. ;

Chin, Ken Lee ;

Chung, Sheng-Chia ;

Cirillo, Massimo .

LANCET, 2020, 395 (10225) :709-733

[4] Trimethylamine N-Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function [J].

Canyelles, Marina ;

Tondo, Mireia ;

Cedo, Lidia ;

Farras, Marta ;

Carles Escola-Gil, Joan ;

Blanco-Vaca, Francisco .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (10)

[5] Worldwide Epidemiology of Diabetes-Related End-Stage Renal Disease, 2000-2015 [J].

Cheng, Hui-Teng ;

Xu, Xiaoqi ;

Lim, Paik Seong ;

Hung, Kuan-Yu .

DIABETES CARE, 2021, 44 (01) :89-97

[6] Role of oxidized low-density lipoprotein in the atherosclerosis of uremia [J].

Drüeke, TB ;

Khoa, TN ;

Massy, ZA ;

Witko-Sarsat, V ;

Lacour, B ;

Descamps-Latscha, B .

KIDNEY INTERNATIONAL, 2001, 59 :S114-S119

[7]

Dumm NTD, 2001, MEDICINA-BUENOS AIRE, V61, P142

[8] Long-term efficacy and safety of fenofibrate and a statin in the treatment of combined hyperlipidemia [J].

Ellen, RLB ;

McPherson, R .

AMERICAN JOURNAL OF CARDIOLOGY, 1998, 81 (4A) :60B-65B

[9] Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation [J].

Fisher, Timothy S. ;

Lo Surdo, Paola ;

Pandit, Shilpa ;

Mattu, Marco ;

Santoro, Joseph C. ;

Wisniewski, Doug ;

Cummings, Richard T. ;

Calzetta, Alessandra ;

Cubbon, Rose M. ;

Fischer, Paul A. ;

Tarachandani, Anil ;

De Francesco, Raffaele ;

Wright, Samuel D. ;

Sparrow, Carl P. ;

Carfi, Andrea ;

Sitlani, Ayesha .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (28) :20502-20512

[10] Sudden cardiac death in dialysis patients: different causes and management strategies [J].

Genovesi, Simonetta ;

Boriani, Giuseppe ;

Covic, Adrian ;

Vernooij, Robin W. M. ;

Combe, Christian ;

Burlacu, Alexandru ;

Davenport, Andrew ;

Kanbay, Mehmet ;

Kirmizis, Dimitrios ;

Schneditz, Daniel ;

van der Sande, Frank ;

Basile, Carlo .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2021, 36 (03) :396-405

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