Mg and Mg alloys: How comparable are in vitro and in vivo corrosion rates? A review

被引：390
作者：
Sanchez, Adela Helvia Martinez [1 ]
Luthringer, Berengere J. C. [1 ]
Feyerabend, Frank [1 ]
Willumeit, Regine [1 ]
机构：
[1] Helmholtz Zentrum Geesthacht, Inst Mat Res, Dept Struct Res Macromol, D-21502 Geesthacht, Germany
来源：
ACTA BIOMATERIALIA | 2015年 / 13卷
关键词：
Magnesium alloys; In vitro and in vivo corrosion; Biomaterials; Orthopaedics; Biodegradable metallic implants; BIODEGRADABLE MAGNESIUM IMPLANTS; SIMULATED BODY-FLUID; RARE-EARTH ALLOY; ZN-ZR ALLOY; DEGRADATION BEHAVIOR; PURE MAGNESIUM; HEAT-TREATMENT; ELECTROCHEMICAL CORROSION; BIORESORBABLE MAGNESIUM; SURFACE MODIFICATION;
D O I：
10.1016/j.actbio.2014.11.048
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Due to their biodegradability, magnesium and magnesium-based alloys could represent the third generation of biomaterials. However, their mechanical properties and time of degradation have to match the needs of applications. Several approaches, such as choice of alloying elements or tailored microstructure, are employed to tailor corrosion behaviour. Due to the high electrochemical activity of Mg, numerous environmental factors (e.g. temperature and surrounding ion composition) influence its corrosion behaviour, making it unpredictable. Nevertheless, the need of reliable in vitro model(s) to predict in vivo implant degradation is increasing. In an attempt to find a correlation between in vitro and vivo corrosion rates, this review presents a systematic literature survey, as well as an attempt to correlate the different results. (C) 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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页码：16 / 31
页数：16
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