A CARD10-Dependent Tonic Signalosome Activates MALT1 Paracaspase and Regulates IL-17/TNF-α-Driven Keratinocyte Inflammation

被引:17
作者
Israel, Laura [1 ]
Bardet, Maureen [1 ]
Huppertz, Antje [1 ,2 ]
Mercado, Nicolas [1 ]
Ginster, Stefanie [1 ,3 ]
Unterreiner, Adeline [1 ]
Schlierf, Anita [1 ]
Goetschy, Jean Francois [1 ]
Zerwes, Hans-Gunter [1 ]
Roth, Lukas [1 ]
Kolbinger, Frank [1 ]
Bornancin, Frederic [1 ]
机构
[1] Novartis Inst BioMed Res, Novartis Campus, Basel, Switzerland
[2] Roche Pharma Res & Early Dev, Basel, Switzerland
[3] Univ Lausanne, Fac Biol & Med, Lausanne, Switzerland
关键词
PROTEASE ACTIVITY; INHIBITION; CELLS; STIMULATION; GENES;
D O I
10.1016/j.jid.2018.03.1503
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
[No abstract available]
引用
收藏
页码:2075 / 2079
页数:6
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