Green-light-responsive metal-organic frameworks for colorectal cancer treatment

被引：17

作者：

Cornell, Hannah D. ^{[1
,2
]}

Zhu, Yumeng ^{[1
,2
]}

Ilic, Stefan ^{[1
]}

Lidman, Naomei E. ^{[1
]}

Yang, Xiaozhou ^{[1
,2
]}

Matson, John B. ^{[1
,2
]}

Morris, Amanda J. ^{[1
,2
]}

机构：

[1] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA

[2] Virginia Tech, Macromol Innovat Inst, Blacksburg, VA 24061 USA

来源：

CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 34期

基金：

美国国家科学基金会;

关键词：

DRUG-DELIVERY SYSTEMS; AZOBENZENE PHOTOSWITCHES; NANOPARTICLES; NANOCARRIERS; MOF;

D O I：

10.1039/d2cc00591c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, the synthetic methods for preparation of a novel light-responsive metal-organic framework (MOF) UiO-AZB-F are outlined. Upon irradiation with green light, the framework demonstrates controlled release of chemotherapeutic drug cargo with simultaneous breakdown into low toxicity small molecule components.

引用

页码：5225 / 5228

页数：5

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