Nanocomposites Based on PCL and Halloysite Nanotubes Filled with Lysozyme: Effect of Draw Ratio on the Physical Properties and Release Analysis

被引:27
作者
Bugatti, Valeria [1 ]
Viscusi, Gianluca [1 ]
Naddeo, Carlo [1 ]
Gorrasi, Giuliana [1 ]
机构
[1] Univ Salerno, Dept Ind Engn, Via Giovanni Paolo II 132, I-84084 Salerno, Italy
关键词
halloysite nanotubes; PCL; lysozyme; controlled release; active packaging; FOOD-PACKAGING APPLICATIONS; CLAY NANOTUBES; COVALENT IMMOBILIZATION; SUSTAINED-RELEASE; PROTECTIVE AGENTS; FILMS; PH; ENCAPSULATION; CONFORMATION; DISPERSION;
D O I
10.3390/nano7080213
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Halloysite nanotubes (HNTs) were loaded with lsozyme, as antimicrobial molecule, at a HNTs/lysozyme ratio of 1:1. Such a nano-hybrid was incorporated into a poly (epsilon-caprolactone) (PCL) matrix at 10 wt % and films were obtained. The nano-composites were submitted to a cold drawn process at three different draw ratios, lambda = 3, 4, and 5, where lambda is l((final length))/ l0((initial length)). Morphology, physical, and barrier properties of the starting nanocomposite and drawn samples were studied, and correlated to the release of the lysozyme molecule. It was demonstrated that with a simple mechanical treatment it is possible to obtain controlled release systems for specific active packaging requirements.
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页数:12
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