Acaricidal daphnane diterpenoids from Trigonostemon reidioides (KURZ) CRAIB roots

被引：40
作者：
Soonthornchareonnon, N [1 ]
Sakayarojkul, M
Isaka, M
Mahakittikun, V
Chuakul, W
Wongsinkongman, P
机构：
[1] Mahidol Univ, Fac Pharm, Dept Pharmacognosy, Bangkok 10400, Thailand
[2] Natl Ctr Genet Engn & Biotechnol, BIOTEC, Pathum Thani 12120, Thailand
[3] Mahidol Univ, Dept Parasitol, Fac Med, Siriraj Hosp, Bangkok 10700, Thailand
[4] Mahidol Univ, Dept Pharmaceut Bot, Fac Pharm, Bangkok 10400, Thailand
[5] Minist Publ Hlth, Dept Med Sci, Bangkok 11000, Thailand
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2005年 / 53卷 / 02期
关键词：
Trigonostemon redioides; acaricidal activity; rediocide; daphnane diterpenoid;
D O I：
10.1248/cpb.53.241
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new daphnane diterpenoid, rediocide F (1), was isolated together with three known compounds, rediocides A (2), C (3) and E (4), from the hexane extract of Trigonostemon reidioides roots by bioassay-guided fractionation for acaricidal activity on Dermatophagoides pteronyssinus, Thai common house dust mite. The structure of rediocide F (1) was established as the demethyl analog of rediocide C (3) on the basis of spectral analysis. Compounds 1-4 exhibited potent activity against D. pteronyssinus with respective LC50 values of 2.53, 0.78, 5.59 and 0.92 mug/cm(2).
引用
收藏
页码：241 / 243
页数：3
相关论文
共 15 条
  • [1] REDUCING DOMESTIC EXPOSURE TO DUST MITE ALLERGEN REDUCES BRONCHIAL HYPERREACTIVITY IN SENSITIVE CHILDREN WITH ASTHMA
    EHNERT, B
    LAUSCHADENDORF, S
    WEBER, A
    BUETTNER, P
    SCHOU, C
    WAHN, U
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 90 (01) : 135 - 138
  • [2] Rediocides B-E, potent insecticides from Trigonostemon reidioides
    Jayasuriya, H
    Zink, DL
    Borris, RP
    Nanakorn, W
    Beck, HT
    Balick, MJ
    Goetz, MA
    Gregory, L
    Shoop, WL
    Singh, SB
    [J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (02): : 228 - 231
  • [3] Structure and stereochemistry of rediocide A, a highly modified daphnane from Trigonostemon reidioides exhibiting potent insecticidal activity
    Jayasuriya, H
    Zink, DL
    Singh, SB
    Borris, RP
    Nanakorn, W
    Beck, HT
    Balick, MJ
    Goetz, MA
    Slayton, L
    Gregory, L
    Zakson-Aiken, M
    Shoop, W
    Singh, SB
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (20) : 4998 - 4999
  • [4] The effectiveness of benzyl benzoate and different chemicals as acaricides
    Kalpaklioglu, AF
    Ferizli, AG
    Misirligil, Z
    Demirel, YS
    Gurbuz, L
    [J]. ALLERGY, 1996, 51 (03) : 164 - 170
  • [5] Lotthanongine, an unprecedented flavonoidal indole alkaloid from the roots of Thai medicinal plant, Trigonostemon reidioides
    Kanchanapoom, T
    Kasai, R
    Chumsri, P
    Kraisintu, K
    Yamasaki, K
    [J]. TETRAHEDRON LETTERS, 2002, 43 (16) : 2941 - 2943
  • [6] STRUCTURE OF TRIGONOSTEMONE, A NEW PHENANTHRENONE FROM THE THAI PLANT TRIGONOSTEMON-REIDIOIDES
    KOKPOL, U
    THEBPATIPHAT, S
    BOONYARATAVEJ, S
    CHEDCHUSKULCAI, V
    NI, CZ
    CLARDY, J
    CHAICHANTIPYUTH, C
    CHITTAWONG, V
    MILES, DH
    [J]. JOURNAL OF NATURAL PRODUCTS, 1990, 53 (05): : 1148 - 1151
  • [7] MAHAKITTIKUN V, 2003, J TROP MED PARASITOL, V26, P93
  • [8] THE ROLE OF WATER TEMPERATURE AND LAUNDRY PROCEDURES IN REDUCING HOUSE DUST MITE POPULATIONS AND ALLERGEN CONTENT OF BEDDING
    MCDONALD, LG
    TOVEY, E
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 90 (04) : 599 - 608
  • [9] THE EFFECTIVENESS OF BENZYL BENZOATE AND SOME ESSENTIAL PLANT OILS AS LAUNDRY ADDITIVES FOR KILLING HOUSE-DUST MITES
    MCDONALD, LG
    TOVEY, E
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1993, 92 (05) : 771 - 772
  • [10] REDUCTION OF HOUSE DUST MITE ALLERGEN LEVELS IN THE HOME - USE OF THE ACARICIDE, PRIMIPHOS METHYL
    MITCHELL, EB
    WILKINS, S
    DEIGHTON, JM
    PLATTSMILLS, TAE
    [J]. CLINICAL ALLERGY, 1985, 15 (03): : 235 - 240
12