Norwood procedure for hypoplastic left heart syndrome: BT shunt or RV-PA conduit?

被引:21
作者
Edwards, Linda
Morris, Kevin P.
Siddiqui, Ameen
Harrington, Deborah
Barron, David
Brawn, William
机构
[1] Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
[2] Childrens Hosp, NHS Trust, Dept Cardiac Surg, Birmingham B4 6NH, W Midlands, England
来源
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 2007年 / 92卷 / 03期
关键词
D O I
10.1136/adc.2006.094664
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background: The Norwood procedure is the first stage palliative procedure for hypoplastic left heart syndrome (HLHS). Traditionally the pulmonary circulation has been supplied via a modified Blalock Taussig (BT) shunt but a recent modification, adopted in some UK centres, substitutes a conduit between right ventricle and pulmonary arteries (RV-PA conduit). It is argued that this will result in a more favourable balance between pulmonary and systemic circulations. Aim: To compare the early postoperative haemodynamic profile between patients undergoing a BT shunt or an RV-PA conduit. Methods: Retrospective review in a tertiary referral PICU of 51 children with HLHS undergoing the Norwood procedure with either a BT shunt (Group 1; n = 23) or an RV-PA conduit (Group 2; n = 28). Data items were extracted at 10 set time points in the initial 96 h, postoperatively. Results: Diastolic BP was significantly lower in Group 1 (p < 0.001) with a trend towards a higher systolic BP and no difference in mean BP. No between-group differences were found in markers of pulmonary blood flow (PaO2, PaCO2, PaO2/FiO(2) ratio), or in markers of systemic blood flow (blood lactate, oxygen extraction ratio), or in estimated ratio of pulmonary: systemic blood flow (Qp:Qs). Despite lower diastolic blood pressure in Group 1 renal and hepatic function did not differ over five post-operative days between groups. Conclusions: With the exception of a higher diastolic blood pressure in the RV-PA conduit group, we found no difference in the early haemodynamic profile between patients undergoing an RV-PA conduit or a BT shunt.
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页码:F210 / F214
页数:5
相关论文
共 17 条
[1]   Evolving strategies and improving outcomes of the modified Norwood procedure: A 10-year single-institution experience [J].
Azakie, A ;
Merklinger, SL ;
McCrindle, BW ;
Van Arsdell, GS ;
Lee, KJ ;
Benson, LN ;
Coles, JG ;
Williams, WG .
ANNALS OF THORACIC SURGERY, 2001, 72 (04) :1349-1353
[2]  
Bando K, 1996, ANN THORAC SURG, V62, P70, DOI 10.1016/0003-4975(96)00251-2
[3]   BALANCING THE CIRCULATION - THEORETIC OPTIMIZATION OF PULMONARY/SYSTEMIC FLOW RATIO IN HYPOPLASTIC LEFT-HEART SYNDROME [J].
BARNEA, O ;
AUSTIN, EH ;
RICHMAN, B ;
SANTAMORE, WP .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1994, 24 (05) :1376-1381
[4]   Results after Norwood procedure and subsequent cavopulmonary anastomoses for typical hypoplastic left heart syndrome and similar complex cardiovascular malformations [J].
Breymann, T ;
Kirchner, G ;
Blanz, U ;
Cherlet, E ;
Knobl, H ;
Meyer, H ;
Körfer, R ;
Thies, WR .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1999, 16 (02) :117-124
[5]   Postoperative hemodynamics after Norwood palliation for hypoplastic left heart syndrome [J].
Charpie, JR ;
Dekeon, MK ;
Goldberg, CS ;
Mosca, RS ;
Bove, EL ;
Kulik, TJ .
AMERICAN JOURNAL OF CARDIOLOGY, 2001, 87 (02) :198-202
[6]   Venous saturation and the anaerobic threshold in neonates after the Norwood procedure for hypoplastic left heart syndrome [J].
Hoffman, GM ;
Ghanayem, NS ;
Kampine, JM ;
Berger, S ;
Mussatto, KA ;
Litwin, SB ;
Tweddell, JS .
ANNALS OF THORACIC SURGERY, 2000, 70 (05) :1515-1520
[7]   Prophylactic intravenous use of Milrinone after cardiac operation in Pediatrics (PRIMACORP) study [J].
Hoffman, TM ;
Wernovsky, G ;
Atz, AM ;
Bailey, JM ;
Akbary, A ;
Kocsis, JF ;
Nelson, DP ;
Chang, AC ;
Kulik, TJ ;
Spray, TL ;
Wessel, DL .
AMERICAN HEART JOURNAL, 2002, 143 (01) :15-21
[8]   CARBON-DIOXIDE PREVENTS PULMONARY OVERCIRCULATION IN HYPOPLASTIC LEFT HEART SYNDROME [J].
JOBES, DR ;
NICOLSON, SC ;
STEVEN, JM ;
MILLER, M ;
JACOBS, ML ;
NORWOOD, WI .
ANNALS OF THORACIC SURGERY, 1992, 54 (01) :150-151
[9]   Hemodynamic profile after the Norwood procedure with right ventricle to pulmonary artery conduit [J].
Maher, KO ;
Pizarro, C ;
Gidding, SS ;
Januszewska, K ;
Malec, E ;
Norwood, WI ;
Murphy, JD .
CIRCULATION, 2003, 108 (07) :782-784
[10]   Right ventricular to pulmonary artery conduit instead of modified Blalock-Taussig shunt improves postoperative hemodynamics in newborns after the Norwood operation [J].
Mair, R ;
Tulzer, G ;
Sames, E ;
Gitter, R ;
Lechner, E ;
Steiner, J ;
Hofer, A ;
Geiselseder, G ;
Gross, C .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2003, 126 (05) :1378-1384