Norwood procedure for hypoplastic left heart syndrome: BT shunt or RV-PA conduit?
被引:21
作者:
Edwards, Linda
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Edwards, Linda
Morris, Kevin P.
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Morris, Kevin P.
Siddiqui, Ameen
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Siddiqui, Ameen
Harrington, Deborah
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Harrington, Deborah
Barron, David
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Barron, David
Brawn, William
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机构:Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
Brawn, William
机构:
[1] Childrens Hosp, NHS Trust, Paediat Intens Care Unit, Dept Paediat Intens Care, Birmingham B4 6NH, W Midlands, England
[2] Childrens Hosp, NHS Trust, Dept Cardiac Surg, Birmingham B4 6NH, W Midlands, England
来源:
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
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2007年
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92卷
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03期
关键词:
D O I:
10.1136/adc.2006.094664
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Background: The Norwood procedure is the first stage palliative procedure for hypoplastic left heart syndrome (HLHS). Traditionally the pulmonary circulation has been supplied via a modified Blalock Taussig (BT) shunt but a recent modification, adopted in some UK centres, substitutes a conduit between right ventricle and pulmonary arteries (RV-PA conduit). It is argued that this will result in a more favourable balance between pulmonary and systemic circulations. Aim: To compare the early postoperative haemodynamic profile between patients undergoing a BT shunt or an RV-PA conduit. Methods: Retrospective review in a tertiary referral PICU of 51 children with HLHS undergoing the Norwood procedure with either a BT shunt (Group 1; n = 23) or an RV-PA conduit (Group 2; n = 28). Data items were extracted at 10 set time points in the initial 96 h, postoperatively. Results: Diastolic BP was significantly lower in Group 1 (p < 0.001) with a trend towards a higher systolic BP and no difference in mean BP. No between-group differences were found in markers of pulmonary blood flow (PaO2, PaCO2, PaO2/FiO(2) ratio), or in markers of systemic blood flow (blood lactate, oxygen extraction ratio), or in estimated ratio of pulmonary: systemic blood flow (Qp:Qs). Despite lower diastolic blood pressure in Group 1 renal and hepatic function did not differ over five post-operative days between groups. Conclusions: With the exception of a higher diastolic blood pressure in the RV-PA conduit group, we found no difference in the early haemodynamic profile between patients undergoing an RV-PA conduit or a BT shunt.