Anti-inflammatory effects of prorenin/(pro)renin receptor blockade: Potential mechanisms of action

被引：0
作者：
Nakano, Daisuke [1 ]
Ichihara, Atsuhiro [2 ,3 ]
机构：
[1] Kagawa Univ, Dept Pharmacol, Kagawa, Japan
[2] Keio Univ, Sch Med, Dept Antiageing Med & Endocrinol, Tokyo, Japan
[3] Keio Univ, Sch Med, Dept Internal Med, Tokyo, Japan
来源：
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2010年 / 37卷 / 03期
关键词：
PRO RENIN RECEPTOR; HANDLE-REGION; DIABETIC-NEPHROPATHY; PRORENIN; PEPTIDE; INTERLEUKIN-6; ACTIVATION; RESPONSES; MARKERS; INJURY;
D O I：
10.1111/j.1440-1681.2009.05340.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：275 / 276
页数：2
相关论文
共 26 条
[1]   Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension [J].
Crowley, Steven D. ;
Frey, Campbell W. ;
Gould, Samantha K. ;
Griffiths, Robert ;
Ruiz, Phillip ;
Burchette, James L. ;
Howell, David N. ;
Makhanova, Natalia ;
Yan, Ming ;
Kim, Hyung-Suk ;
Tharaux, Pierre-Louis ;
Coffman, Thomas M. .
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2008, 295 (02) :F515-F524
[2]   The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling [J].
Feldt, Sandra ;
Maschke, Ulrike ;
Dechend, Ralf ;
Luft, Friedrich C. ;
Muller, Dominik N. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2008, 19 (04) :743-748
[3]   Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide [J].
Feldt, Sandra ;
Batenburg, Wendy W. ;
Mazak, Istvan ;
Maschke, Ulrike ;
Wellner, Maren ;
Kvakan, Heda ;
Dechend, Ralf ;
Fiebeler, Anette ;
Burckle, Celine ;
Contrepas, Aurelie ;
Danser, A. H. Jan ;
Bader, Michael ;
Nguyen, Genevieve ;
Luft, Friedrich C. ;
Muller, Dominik N. .
HYPERTENSION, 2008, 51 (03) :682-688
[4]   HUMAN PRORENIN [J].
HSUEH, WA ;
BAXTER, JD .
HYPERTENSION, 1991, 17 (04) :469-479
[5]   Renin increases mesangial cell transforming growth factor-β1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms [J].
Huang, Y ;
Wongamorntham, S ;
Kasting, J ;
McQuillan, D ;
Owens, RT ;
Yu, L ;
Noble, NA ;
Border, W .
KIDNEY INTERNATIONAL, 2006, 69 (01) :105-113
[6]   Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle'' region for nonproteolytic activation of prorenin [J].
Ichihara, A ;
Hayashi, M ;
Kaneshiro, Y ;
Suzuki, F ;
Nakagawa, T ;
Tada, Y ;
Koura, Y ;
Nishiyama, A ;
Okada, H ;
Uddin, MN ;
Nabi, AHMN ;
Ishida, Y ;
Inagami, T ;
Saruta, T .
JOURNAL OF CLINICAL INVESTIGATION, 2004, 114 (08) :1128-1135
[7]   Contribution of nonproteolytically activated prorenin in glomeruli to hypertensive renal damage [J].
Ichihara, Atsuhiro ;
Kaneshiro, Yuki ;
Takemitsu, Tomoko ;
Sakoda, Mariyo ;
Nakagawa, Tsutomu ;
Nishiyama, Akira ;
Kawachi, Hiroshi ;
Shimizu, Fujio ;
Inagami, Tadashi .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (09) :2495-2503
[8]   Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice [J].
Ichihara, Atsuhiro ;
Suzuki, Fumiaki ;
Nakagawa, Tsutomu ;
Kaneshiro, Yuki ;
Takemitsu, Tomoko ;
Sakoda, Mariyo ;
Nabi, A. H. M. Nurun ;
Nishiyama, Akira ;
Sugaya, Takeshi ;
Hayashi, Matsuhiko ;
Inagami, Tadashi .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (07) :1950-1961
[9]   DOES THE INTRARENAL REACTIVE OXYGEN SPECIES/ANGIOTENSINOGEN/RENIN-ANGIOTENSIN SYSTEM AXIS PLAY AN IMPORTANT ROLE IN THE PROGRESSION OF CHRONIC KIDNEY DISEASE? [J].
Konishi, Yoshio ;
Imanishi, Masahito .
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2009, 36 (08) :748-749
[10]   Increased glycated albumin and decreased esRAGE levels are related to angiographic severity and extent of coronary artery disease in patients with type 2 diabetes [J].
Lu, Lin ;
Pu, Li Jin ;
Zhang, Qi ;
Wang, Ling Jie ;
Kang, Sheng ;
Zhang, Rui Yan ;
Chen, Qiu Jing ;
Wang, Ji Guang ;
De Caterina, Raffaele ;
Shen, Wei Feng .
ATHEROSCLEROSIS, 2009, 206 (02) :540-545
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