Individual Field Simultaneous Optimization (IFSO) in spot scanning proton therapy of head and neck cancers

被引:10
作者
Anand, Aman [1 ]
Bues, Martin [1 ]
Gamez, Mauricio E. [1 ]
Stefan, Corbin [1 ]
Patel, Samir H. [1 ]
机构
[1] Mayo Clin, Dept Radiat Oncol, 5881 E Mayo Blvd, Phoenix, AZ 85054 USA
关键词
Proton therapy; Head and neck cancer; Scanning proton therapy; Individual Field Simultaneous Optimization (IFSO); INTENSITY-MODULATED PHOTON; RANGE UNCERTAINTIES; RADIOTHERAPY; REDUCTION;
D O I
10.1016/j.meddos.2019.02.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In order to better spare organs at risk in the head and neck, the application of proton beam therapy is of great interest. In this study we report the clinical utilization of a novel and robust scanning proton beam therapy treatment planning method called Individual Field Simultaneous Optimization (IFSO) that incorporates the advantages of field patching technique integrated with simultaneous optimization of multiple fields. A treatment planning intercomparison between a conventional Intensity Modulated Proton Therapy Treatment Plan with single target volume vs a split target volume utilizing IFSO method demonstrates superiority of IFSO with regards to sparing of organs at risk and plan robustness. (C) 2019 Published by Elsevier Inc. on behalf of American Association of Medical Dosimetrists.
引用
收藏
页码:375 / 378
页数:4
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