Melatonin secretion after surgery

被引：112
作者：
Cronin, AJ
Keifer, JC
Davies, MF
King, TS
Bixler, EO
机构：
[1] Penn State Univ, Milton S Hershey Med Ctr, Dept Anesthesiol, Hershey, PA 17033 USA
[2] Penn State Univ, Milton S Hershey Med Ctr, Dept Obstet & Gynecol, Hershey, PA 17033 USA
[3] Penn State Univ, Milton S Hershey Med Ctr, Dept Hlth Evaluat Sci, Hershey, PA 17033 USA
[4] Penn State Univ, Milton S Hershey Med Ctr, Dept Psychiat, Hershey, PA 17033 USA
[5] Duke Univ, Med Ctr, Dept Anesthesiol, Durham, NC 27710 USA
来源：
LANCET | 2000年 / 356卷 / 9237期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0140-6736(00)02795-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.
引用
收藏
页码：1244 / 1245
页数：2
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