Convenient selective synthesis of 5,7,8,9-tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones

被引：2

作者：

Litvinov, Yu. M. ^{[1
]}

Shestopalov, A. M. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2009年 / 58卷 / 02期

关键词：

chromeno[2,3-d][1,3]oxazin-4-ones; ethyl; 2-amino-4H-pyran-3-carboxylates; annulated heterocycles; acylation; acid catalysis; HUMAN-LEUKOCYTE ELASTASE; DERIVATIVES; INHIBITORS;

D O I：

10.1007/s11172-010-0037-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the synthesis of 5,7,8,9-tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones was developed. The method involves acid-catalyzed acylation of substituted ethyl 2-amino-4-aryl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates with acetic anhydride.

引用

页码：479 / 481

页数：3

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