Convenient selective synthesis of 5,7,8,9-tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones

被引：2
作者：
Litvinov, Yu. M. [1 ]
Shestopalov, A. M. [1 ]
机构：
[1] Russian Acad Sci, ND Zelinskii Organ Chem Inst, Moscow 119991, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2009年 / 58卷 / 02期
关键词：
chromeno[2,3-d][1,3]oxazin-4-ones; ethyl; 2-amino-4H-pyran-3-carboxylates; annulated heterocycles; acylation; acid catalysis; HUMAN-LEUKOCYTE ELASTASE; DERIVATIVES; INHIBITORS;
D O I：
10.1007/s11172-010-0037-z
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for the synthesis of 5,7,8,9-tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones was developed. The method involves acid-catalyzed acylation of substituted ethyl 2-amino-4-aryl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylates with acetic anhydride.
引用
收藏
页码：479 / 481
页数：3
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