A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium

被引：26
作者：
Wang, Kui [1 ]
Cui, Jian-Hua [1 ]
Xing, Si-Yang [1 ]
Ren, Xiao-Wei [1 ]
机构：
[1] Tianjin Normal Univ, Tianjin Key Lab Struct & Performance Funct Mol, Key Lab Inorgan Organ Hybrid Funct Mat Chem, Minist Educ,Coll Chem, Tianjin 300387, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 54期
基金：
中国国家自然科学基金;
关键词：
CONTROLLED-RELEASE; SUPRA-AMPHIPHILES; BUILDING-BLOCKS; IN-VIVO; HOST; HYALURONAN; COPOLYMER; VESICLES; DELIVERY; STIMULI;
D O I：
10.1039/c7cc02693e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have successfully constructed a supramolecular assembly based on the anionic recognition of calixpyridinium for the first time employing native biocompatible polysaccharide hyaluronan as the guest, which showed hyaluronidase-responsive disassembly and temperature-responsive morphological conversion from a nanosphere to a nanosquare upon increasing the temperature.
引用
收藏
页码：7517 / 7520
页数：4
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