Using molecular markers in sputum for the early detection of lung cancer: A review

被引：18
|
作者：
Kennedy, TC [1 ]
Hirsch, FR [1 ]
机构：
[1] Univ Colorado, Ctr Canc, Specialized Program Res Excellence, NCI, Denver, CO 80262 USA
来源：
LUNG CANCER | 2004年 / 45卷
关键词：
non-small-cell lung carcinoma; sputum; biological markers;
D O I：
10.1016/j.lungcan.2004.07.996
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent exciting advances have been made in identifying potential molecular markers in sputum which may soon be ready for validation trials to indicate high risk for lung cancer, especially central airway squamous cell lung cancer. Hopefully, a set of biomarkers will. be identified with higher sensitivity, specificity, and enough lead-time compared to traditional cytopathology to justify endobronchial evaluation and local therapy to help reduce lung-cancer mortality in high-risk patients. (C) 2004 Elsevier Science Ltd.
引用
收藏
页码：S21 / S27
页数：7
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