Synteny mapping of four genes from the short arm of human chromosome 19 to bovine chromosome 7

被引：2

作者：

Gu, ZX

Womack, JE

Kirkpatrick, BW ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Anim Sci, Madison, WI 53706 USA

[2] Texas A&M Univ, Dept Vet Pathol, College Stn, TX 77843 USA

来源：

CYTOGENETICS AND CELL GENETICS | 1997年 / 79卷 / 3-4期

关键词：

D O I：

10.1159/000134728

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Four genes on the short arm of human chromosome 19 (HSA 19p) were assigned to bovine chromosome 7 (BTA 7) using a bovine x rodent somatic hybrid cell panel. These four genes were cartilage oligomeric matrix protein (COMP), lymphoblastic leukemia derived sequence 1 (LYL1), lysosomal alpha-mannosidase (MANB), and RAS oncogene family member RAB3A. Bovine sequence tagged sites were developed for the four genes and used for screening a bovine x rodent somatic cell panel. All four genes were mapped to bovine synteny group U22 (BTA 7) with a correlation coefficient of 0.901-1.000. This study confirms that the centromeric region of BTA 7 is conserved with HSA 19p.

引用

页码：225 / 227

页数：3

共 6 条

[1] STATISTICAL DECISION RULES CONCERNING SYNTENY OR INDEPENDENCE BETWEEN MARKERS [J].