Yale School of Public Health Symposium: An overview of the challenges and opportunities associated with per- and polyfluoroalkyl substances (PFAS)

被引:23
作者
Hagstrom, Anna L. [1 ,2 ]
Anastas, Paul [3 ,4 ]
Boissevain, Andrea [3 ,5 ]
Borrel, Alexandre [6 ]
Deziel, Nicole C. [3 ]
Fenton, Suzanne E. [7 ]
Fields, Cheryl [8 ]
Fortner, John D. [9 ]
Franceschi-Hofmann, Nikolas [10 ]
Frigon, Raymond [1 ]
Jin, Lan [11 ]
Kim, Jae-Hong [9 ]
Kleinstreuer, Nicole C. [6 ,12 ]
Koelmel, Jeremy [3 ]
Lei, Yu [13 ]
Liew, Zeyan [3 ]
Ma, Xiuqi [3 ]
Mathieu, Lori [8 ]
Nason, Sara L. [14 ]
Organtini, Kari [15 ]
Oulhote, Youssef [16 ]
Pociu, Shannon [1 ]
Pollitt, Krystal J. Godri [3 ]
Saiers, James [4 ]
Thompson, David C. [17 ]
Toal, Brian [8 ]
Weiner, Eric J. [18 ]
Whirledge, Shannon [3 ,19 ]
Zhang, Yawei [3 ]
Vasiliou, Vasilis [3 ]
机构
[1] Connecticut Dept Energy & Environm Protect, Hartford, CT USA
[2] Connecticut Acad Sci & Engn, Rocky Hill, CT USA
[3] Yale Sch Publ Hlth, Dept Environm Hlth Sci, 60 Coll St, New Haven, CT 06510 USA
[4] Yale Sch Environm, New Haven, CT USA
[5] Stratford Hlth Dept, Stratford, CT USA
[6] NIEHS, NIH, DIR Biostat & Computat Biol Branch, POB 12233, Res Triangle Pk, NC 27709 USA
[7] NIEHS, NIH, Div Natl Toxicol Program, NTP Lab, POB 12233, Res Triangle Pk, NC 27709 USA
[8] Connecticut Dept Publ Hlth, Hartford, CT USA
[9] Yale Univ, Dept Chem & Environm Engn, New Haven, CT USA
[10] Aqualumos, Killingworth, CT USA
[11] Yale Sch Med, Dept Surg, New Haven, CT USA
[12] NIEHS, NIH, Div Natl Toxicol Program, NTP Interagency Ctr Evaluat Alternat Toxicol Meth, POB 12233, Res Triangle Pk, NC 27709 USA
[13] Univ Connecticut, Sch Engn, Dept Chem & Biomol Engn, Storrs, CT USA
[14] Connecticut Agr Expt Stn, New Haven, CT 06504 USA
[15] Waters Corp, Milford, MA USA
[16] Univ Massachusetts, Sch Publ Hlth & Hlth Sci, Amherst, MA 01003 USA
[17] Univ Colorado, Skaggs Sch Pharm & Pharmaceut Sci, Dept Clin Pharm, Aurora, CO USA
[18] Windsor Climate Act, Clean Water Task Force, Windsor, CT USA
[19] Yale Sch Med, Dept Obstet Gynecol & Reprod Sci, New Haven, CT USA
关键词
Per- and polyfluoroalkyl substances (PFAS); Exposure; Health effects; Environmental contamination; Drinking water; PERFLUOROOCTANOIC ACID PFOA; ATTENTION DEFICIT/HYPERACTIVITY DISORDER; GESTATIONAL DIABETES-MELLITUS; DRINKING-WATER CONTAMINANTS; EVIDENCE-BASED MEDICINE; DRIED BLOOD SPOTS; PERFLUOROALKYL SUBSTANCES; PRENATAL EXPOSURE; CORD BLOOD; FLUORINATED ALTERNATIVES;
D O I
10.1016/j.scitotenv.2021.146192
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
On December 13, 2019, the Yale School of Public Health hosted a symposium titled "Per- and Polyfluoroalkyl Substances (PFAS): Challenges and Opportunities" in New Haven, Connecticut. The meeting focused on the current state of the science on these chemicals, highlighted the challenges unique to PFAS, and explored promising opportunities for addressing them. It brought together participants from Yale University, the National Institute of Environmental Health Sciences, the University of Massachusetts Amherst, the University of Connecticut, the Connecticut Agricultural Experiment Station, the Connecticut Departments of Public Health and Energy and Environmental Protection, and the public and private sectors. Presentations during the symposium centered around several primary themes. The first reviewed the current state of the science on the health effects associated with PFAS exposure and noted key areas that warranted future research. As research in this field relies on specialized laboratory analyses, the second theme considered commercially available methods for PFAS analysis as well as several emerging analytical approaches that support health studies and facilitate the investigation of a broader range of PFAS. Since mitigation of PFAS exposure requires prevention and cleanup of contamination, the third theme highlighted new nanotechnology-enabled PFAS remediation technologies and explored the potential of green chemistry to develop safer alternatives to PFAS. The fourth theme covered collaborative efforts to assess the vulnerability of in-state private wells and small public water supplies to PFAS contamination by adjacent landfills, and the fifth focused on strategies that promote successful community engagement. This symposium supported a unique interdisciplinary coalition established during the development of Connecticut's PFAS Action Plan, and discussions occurring throughout the symposium revealed opportunities for collaborations among Connecticut scientists, state and local officials, and community advocates. In doing so, it bolstered the State of Connecticut's efforts to implement the ambitious initiatives that its PFAS Action Plan recommends. (C) 2021 Published by Elsevier B.V.
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页数:13
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