Alcohol use and mortality in older men and women

被引:33
作者
McCaul, Kieran A. [1 ,2 ,3 ]
Almeida, Osvaldo P. [1 ,2 ,4 ,5 ,6 ]
Hankey, Graeme J.
Jamrozik, Konrad [7 ]
Byles, Julie E. [8 ]
Flicker, Leon [1 ,2 ,3 ,9 ]
机构
[1] Univ Western Australia, Med Res Ctr, Western Australian Ctr Hlth & Ageing, Perth, WA 6009, Australia
[2] Western Australian Inst Med Res, Perth, WA, Australia
[3] Univ Western Australia, WA Ctr Hlth & Ageing M573, Sch Med & Pharmacol, Crawley, WA 6009, Australia
[4] Univ Western Australia, Sch Psychiat & Clin Neurosci, Crawley, WA 6009, Australia
[5] Royal Perth Hosp, Dept Psychiat, Perth, WA, Australia
[6] Royal Perth Hosp, Dept Neurol, Stroke Unit, Perth, WA, Australia
[7] Univ Adelaide, Sch Populat Hlth & Clin Practice, Adelaide, SA, Australia
[8] Univ Newcastle, Fac Hlth, Res Ctr Gender Hlth & Ageing, Newcastle, NSW 2308, Australia
[9] Royal Perth Hosp, Dept Geriatr Med, Perth, WA, Australia
基金
英国医学研究理事会;
关键词
Aged; alcohol consumption; cause of death; cohort studies; drinking patterns; gender differences; mortality; CORONARY-HEART-DISEASE; CARDIOVASCULAR-DISEASE; LIFETIME ABSTAINERS; CONSUMPTION; RISK; PATTERNS; DRINKING; HEALTH; COHORT; ADULTS;
D O I
10.1111/j.1360-0443.2010.02972.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Aims To compare the effect of alcohol intake on 10-year mortality for men and women over the age of 65 years. Design, setting and participants Two prospective cohorts of community-dwelling men aged 65-79 years at baseline in 1996 (n = 11 727) and women aged 70-75 years in 1996 (n = 12 432). Measurements Alcohol was assessed according to frequency of use (number of days alcohol was consumed per week) and quantity consumed per day. Cox proportional hazards models were compared for men and women for all-cause and cause-specific mortality. Findings Compared with older adults who did not consume alcohol every week, the risk of all-cause mortality was reduced in men reporting up to four standard drinks per day and in women who consumed one or two drinks per day. One or two alcohol-free days per week reduced this risk further in men, but not in women. Similar results were observed for deaths due to cardiovascular disease. Conclusions In people over the age of 65 years, alcohol intake of four standard drinks per day for men and two standard drinks per day for women was associated with lower mortality risk. For men, the risk was reduced further if accompanied with 1 or 2 alcohol-free days per week.
引用
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页码:1391 / 1400
页数:10
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