Comparative Evaluation of Uroflowmetric Parameters in Patients with Benign Prostatic Hyperplasia Undergoing Transurethral Resection of the Prostate

Introduction: Benign Prostatic Hyperplasia (BPH) is a common disorder affecting elderly men which substantially impacts Quality of Life (QoL) mainly due to Lower Urinary Tract Symptoms (LUTS). Aim: This study assessed the role of uroflowmetry in LUTS evaluation due to BPH and use of uroflowmetry before and after Transurethral Resection of the Prostate (TURP). Materials and Methods: This was a prospective single centre study conducted between November 2016 and May 2018. Patients aged more than 40 years who presented with LUTS due to BPH and were recommended to undergo TURP were eligible for participation. International Prostate Symptomatic Score (IPSS) and uroflowmetric data was collected pre and postoperatively (Day 7, 30 and 90). Chi-Square, crosstabs, paired-t, repeated measure ANOVA, and Pearson's correlation coefficient tests were used. Results: A total of 50 patients were included in the study. The mean (SD) age was 67.62 (8.63) years and a total of 20 (40%) patients were aged between 61 to 70 years. Postoperatively, significant (p<0.0001) improvement was observed in the IPSS score with 3 (6%) patients having values <8, 47 (94%) patients having values between 9-19 and none had >20. Postoperatively, maximum flow rate (Q(max)), average flow rate (Q(avg)), and time taken for voiding maximum volume/second (T-max) improved significantly (p<0.0001). Among IPSS QoL parameters the greatest improvement was found for incomplete emptying, intermittency, weak stream, and straining. Conclusion: Uroflowmetry parameters can be used to assess the symptoms as well as to predict the outcome of TURP. The IPSS is valuable in assessing the symptom complex of LUTS with BPH.