Steroidal saponins from Dracaena surculosa

被引：45

作者：

Yokosuka, A ^{[1
]}

Mimaki, Y ^{[1
]}

Sashida, A ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Hachioji, Tokyo 1920392, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 09期

关键词：

D O I：

10.1021/np000145j

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A phytochemical investigation of the whole plant of Dracaena surculosa resulted in the isolation of nine steroidal saponins, including three new bisdesmosidic spirostanol saponins, named surculosides A (1), B (2), and C (3), and a new bisdesmosidic furostanol saponin (4), which are based on (25S)-spirost-5-ene-1 beta,3 beta-diol [(25S)-ruscogenin] as the aglycon. The structures of 1-4 were determined by spectroscopic analysis, including 2D NMR spectroscopic data, and the results of hydrolytic cleavage. The isolated saponins we re evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells.

引用

页码：1239 / 1243

页数：5

共 19 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].