Hydrogen/Deuterium Exchange Reactions of Olefins with Deuterium Oxide Mediated by the Carbonylchlorohydridotris(triphenylphosphine)ruthenium(II) Complex

被引：61
作者：
Tse, Sunny Kai San [1 ]
Xue, Peng [1 ]
Lin, Zhenyang [1 ]
Jia, Guochen [1 ]
机构：
[1] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 09期
关键词：
alkenes; hydrides; isotopes; osmium; ruthenium; C-H ACTIVATION; HYDROGEN ISOTOPE-EXCHANGE; CATALYZED H/D EXCHANGE; BIMETALLIC RUTHENIUM COMPLEXES; TRANSITION-METAL HYDRIDE; INSERTION REACTIONS; DIHYDROGEN COMPLEXES; BOND ACTIVATION; REGIOSELECTIVE DEUTERATION; ORGANOMETALLIC CHEMISTRY;
D O I：
10.1002/adsc.201000037
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The catalytic properties of several ruthenium, osmium and rhodium hydride complexes for hydrogen/deuterium (H/D) exchange between olefins and deuterium oxide (D2O) were investigated. The most effective catalytic precursor was found to be the carbonylchlorohydridotris(triphenylphosphine)ruthenium(II) complex. Through H/D exchange between metal hydride and D2O, and reversible olefin insertion into an Ru-H(D) bond, protons attached to olefinic carbons and alkyl chains of olefins can all undergo H/D exchange with D2O. The catalytic reactions can be used to deuterate both terminal and internal olefins, for example, styrene, stilbene and cyclooctene.
引用
收藏
页码：1512 / 1522
页数：11
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