Total syntheses of (+)-lyconadin A and (-)-lyconadin B

被引：70

作者：

Beshore, Douglas C.

Smith, Amos B., III ^{[1
]}

机构：

[1] Univ Penn, Lab Res Struct Matter, Dept Chem, Philadelphia, PA 19104 USA

[2] Univ Penn, Monell Chem Senses Ctr, Philadelphia, PA 19104 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 14期

关键词：

D O I：

10.1021/ja070336+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enantioselective syntheses of (+)-lyconadin A and (-)-lyconadin B are described. Key bond constructions include a strategy-level intramolecular aldol/conjugate addition cascade, an olefin aminoiodination, and a novel one-pot alpha-pyridinone annulation.

引用

页码：4148 / +

页数：3

共 16 条

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