Total syntheses of (+)-lyconadin A and (-)-lyconadin B

被引：70
作者：
Beshore, Douglas C.
Smith, Amos B., III [1 ]
机构：
[1] Univ Penn, Lab Res Struct Matter, Dept Chem, Philadelphia, PA 19104 USA
[2] Univ Penn, Monell Chem Senses Ctr, Philadelphia, PA 19104 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 14期
关键词：
D O I：
10.1021/ja070336+
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The enantioselective syntheses of (+)-lyconadin A and (-)-lyconadin B are described. Key bond constructions include a strategy-level intramolecular aldol/conjugate addition cascade, an olefin aminoiodination, and a novel one-pot alpha-pyridinone annulation.
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页码：4148 / +
页数：3
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