Biotransformation of implanted coral in some animals studied by neutron activation analysis

被引:2
作者
Irigaray, JL [1 ]
Oudadesse, H [1 ]
Sauvage, T [1 ]
机构
[1] Univ Blaise Pascal, CNRS, Lab Phys Corpusculaire Clermont Ferrand, IN2P3, F-63177 Clermont Ferrand, France
关键词
Physical Chemistry; Inorganic Chemistry; Apatite; Activation Analysis; Biotransformation;
D O I
10.1023/A:1006754702817
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In vivo behavior of biomaterial is dependent on the site of implantation. Characterization by atomic element transfers versus the implantation duration is a quantitative approach to the phenomenon. Here, bioactive coral is implanted in ovine, porcine and rabbit thighbones and not in sheep jawbones as previously reported. Biopsies extracted between 1 and 24 weeks are analysed by fast neutron activation. Mineral composition of the coral is greatly modified: Ca, P, Mg and Sr concentrations become comparable to those of mature bone some months after the implantation. Results suggest a bioactive resorption followed by apatite formation.
引用
收藏
页码:317 / 319
页数:3
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