2.5D Heterogeneously Integrated Microsystem for High-Density Neural Sensing Applications

被引:2
作者
Huang, Po-Tsang [1 ]
Wu, Shang-Lin [1 ]
Huang, Yu-Chieh [1 ]
Chou, Lei-Chun [1 ]
Huang, Teng-Chieh [1 ]
Wang, Tang-Hsuan [1 ]
Lin, Yu-Rou [1 ]
Cheng, Chuan-An [1 ]
Shen, Wen-Wei [1 ]
Chuang, Ching-Te [1 ]
Chen, Kuan-Neng [1 ]
Chiou, Jin-Chern [1 ]
Hwang, Wei [1 ]
Tong, Ho-Ming [1 ]
机构
[1] Natl Chiao Tung Univ, Hsinchu 300, Taiwan
关键词
Analog front-end (AFE); configurable discrete wavelet transform (DWT); low-power ADC; neural sensing microsystem; on-interposer bus; through-silicon-via (TSV); 2.5D heterogeneous integration; mu-probes; SAR ADC; AMPLIFIER; CIRCUIT;
D O I
10.1109/TBCAS.2014.2385061
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Heterogeneously integrated and miniaturized neural sensing microsystems are crucial for brain function investigation. In this paper, a 2.5D heterogeneously integrated bio-sensing microsystem with mu-probes and embedded through-silicon-via (TSVs) is presented for high-density neural sensing applications. This microsystem is composed of mu-probes with embedded TSVs, 4 dies and a silicon interposer. For capturing 16-channel neural signals, a 24 x 24 mu-probe array with embedded TSVs is fabricated on a 5 x 5 mm2 chip and bonded on the back side of the interposer. Thus, each channel contains 6 x 6 mu-probes with embedded TSVs. Additionally, the 4 dies are bonded on the front side of the interposer and designed for biopotential acquisition, feature extraction and classification via low-power analog front-end (AFE) circuits, area-power-efficient analog-to-digital converters (ADCs), configurable discrete wavelet transforms (DWTs), filters, and a MCU. An on-interposer bus (mu-SPI) is designed for transferring data on the interposer. Finally, the successful in-vivo test demonstrated the proposed 2.5D heterogeneously integrated bio-sensing microsystem. The overall power of this microsystem is only 676.3 mu W for 16-channel neural sensing.
引用
收藏
页码:810 / 823
页数:14
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