Design and synthesis of thiazoline-thiazole hybrid macrocycles possessing strong binding affinity to Pb2+ and Cd2+

被引：8
作者：
Han, Fu She [1 ]
Tokuyama, Hidetoshi [1 ]
Fukuyama, Tohru [1 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Japan Sci & Technol Agcy, PRESTO,Bunkyo Ku, Tokyo 1130033, Japan
来源：
CHEMICAL COMMUNICATIONS | 2007年 / 33期
关键词：
D O I：
10.1039/b707904d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Thiazoline-thiazole hybrid macrocycles were synthesized via head-to-tail cyclooligomerization. The macrocycle consisting of eight heterocyclic subunits displays high binding affinity to the heavy metal toxins Pb2+ and Cd2+.
引用
收藏
页码：3444 / 3446
页数：3
相关论文
共 21 条
  • [1] Concise synthesis of stereodefined, thiazole -: containing cyclic hexa- and octapeptide relatives of the Lissoclinums, via cyclooligomerisation reactions
    Bertram, A
    Blake, AJ
    de Turiso, FGL
    Hannam, JS
    Jolliffe, KA
    Pattenden, G
    Skae, M
    [J]. TETRAHEDRON, 2003, 59 (35) : 6979 - 6990
  • [2] Bisson AP, 1998, CHEM-EUR J, V4, P845, DOI 10.1002/(SICI)1521-3765(19980515)4:5<845::AID-CHEM845>3.0.CO
  • [3] 2-#
  • [4] THE CHIRAL SYNTHESIS OF THIAZOLE AMINO-ACID ENANTIOMERS
    BREDENKAMP, MW
    HOLZAPFEL, CW
    VANZYL, WJ
    [J]. SYNTHETIC COMMUNICATIONS, 1990, 20 (15) : 2235 - 2249
  • [5] Breitenbach J., 1996, COMPREHENSIVE SUPRAM, V2, P29
  • [6] DAVIES JED, 1996, COMPREHENSIVE SUPRAM, V8, P435
  • [7] HIGH-FIELD NUCLEAR-MAGNETIC-RESONANCE TECHNIQUES FOR THE INVESTIGATION OF A BETA-CYCLODEXTRIN-INDOMETHACIN INCLUSION COMPLEX
    DJEDAINI, F
    LIN, SZ
    PERLY, B
    WOUESSIDJEWE, D
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1990, 79 (07) : 643 - 646
  • [8] A long-wavelength fluorescent chemodosimeter selective for Cu(II) ion in water
    Dujols, V
    Ford, F
    Czarnik, AW
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (31) : 7386 - 7387
  • [9] Synthetic receptors for carboxylic acids and carboxylates
    Fitzmaurice, RJ
    Kyne, GM
    Douheret, D
    Kilburn, JD
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2002, (07): : 841 - 864
  • [10] ON THE USE OF THE METHOD OF CONTINUOUS VARIATIONS
    GIL, VMS
    OLIVEIRA, NC
    [J]. JOURNAL OF CHEMICAL EDUCATION, 1990, 67 (06) : 473 - 478
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