Arterial stiffness: From surrogate marker to therapeutic target

被引：5
作者：
Van Bortel, Luc [1 ]
机构：
[1] Univ Ghent, Heymans Inst Pharmacol, De Pintelaan 185, B-9000 Ghent, Belgium
来源：
ARTERY RESEARCH | 2016年 / 14卷
关键词：
Pulse wave velocity; Arterial stiffness; Target organ damage; Hypertension guidelines; PULSE-WAVE VELOCITY; ALL-CAUSE MORTALITY; EXPERT CONSENSUS DOCUMENT; AORTIC STIFFNESS; CARDIOVASCULAR EVENTS; CAROTID STIFFNESS; RISK; PREDICTION; DISEASE; FRAMINGHAM;
D O I：
10.1016/j.artres.2016.01.001
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Carotid-femoral (aortic) pulse wave velocity (PWV) is the modern benchmark for the assessment of arterial stiffness. Current European hypertension guidelines acknowledge the good cardiovascular (CV) predictive value, reproducibility and cost-effectiveness of PWV. Aortic PWV is an asset to classical cardiovascular risk scores and can reclassify patients. Reference values for carotid-femoral PWV have been established. Together with standardisation of user procedures and patient conditions, these reference values are needed for an appropriate use of aortic stiffness in daily clinical practice. Finally, the existing evidence for a decrease in CV risk by decreasing aortic stiffness is discussed. (C) 2016 Published by Elsevier B. V. on behalf of Association for Research into Arterial Structure and Physiology.
引用
收藏
页码：10 / 14
页数：5
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