A Review on Properties of Natural and Synthetic Based Electrospun Fibrous Materials for Bone Tissue Engineering

被引：202
作者：
Bhattarai, Deval Prasad [1 ,2 ]
Aguilar, Ludwig Erik [1 ]
Park, Chan Hee [1 ,3 ]
Kim, Cheol Sang [1 ,3 ]
机构：
[1] Chonbuk Natl Univ, Grad Sch, Dept Bionanosyst Engn, Jeonju 561756, South Korea
[2] Tribhuvan Univ, Dept Chem, Amrit Campus, Kathmandu 44613, Nepal
[3] Chonbuk Natl Univ, Div Mech Design Engn, Jeonju 561756, South Korea
来源：
MEMBRANES | 2018年 / 8卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
bone tissue regeneration; electrospinning; biocompatible polymers; nanotechnology; biomimicry; SILK-BASED BIOMATERIALS; NANOFIBROUS SCAFFOLDS; MECHANICAL-PROPERTIES; EXTRACELLULAR-MATRIX; COMPOSITE SCAFFOLDS; PEPTIDE NANOFIBERS; NANOCOMPOSITE SCAFFOLDS; COLLAGEN NANOFIBERS; HYBRID SCAFFOLD; DRUG-DELIVERY;
D O I：
10.3390/membranes8030062
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bone tissue engineering is an interdisciplinary field where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. Among many alternatives, electrospinning is a promising and versatile technique that is used to fabricate polymer fibrous scaffolds for bone tissue engineering applications. Copolymerization and polymer blending is a promising strategic way in purpose of getting synergistic and additive effect achieved from either polymer. In this review, we summarize the basic chemistry of bone, principle of electrospinning, and polymers that are used in bone tissue engineering. Particular attention will be given on biomechanical properties and biological activities of these electrospun fibers. This review will cover the fundamental basis of cell adhesion, differentiation, and proliferation of the electrospun fibers in bone tissue scaffolds. In the last section, we offer the current development and future perspectives on the use of electrospun mats in bone tissue engineering.
引用
收藏
页数：24
相关论文
共 171 条
[81]   Degradation of polymer blends: A brief review [J].
La Mantia, F. P. ;
Morreale, M. ;
Botta, L. ;
Mistretta, M. C. ;
Ceraulo, M. ;
Scaffaro, R. .
POLYMER DEGRADATION AND STABILITY, 2017, 145 :79-92
[82]   Processing of AB-type carbonated hydroxyapatite Ca10-x(PO4)6-x(CO3)x(OH)2-x-2y(CO3)y ceramics with controlled composition [J].
Lafon, J. P. ;
Champion, E. ;
Bernache-Assollant, D. .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2008, 28 (01) :139-147
[83]   TISSUE ENGINEERING [J].
LANGER, R ;
VACANTI, JP .
SCIENCE, 1993, 260 (5110) :920-926
[84]   Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering [J].
Law, Jia Xian ;
Liau, Ling Ling ;
Saim, Aminuddin ;
Yang, Ying ;
Idrus, Ruszymah .
TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2017, 14 (06) :699-718
[85]   Polymers in Biomedicine and Electronics [J].
Lendlein, Andreas ;
Rehahn, Matthias ;
Buchmeiser, Michael R. ;
Haag, Rainer .
MACROMOLECULAR RAPID COMMUNICATIONS, 2010, 31 (17) :1487-1491
[86]   Polymers in Biomedicine [J].
Lendlein, Andreas .
MACROMOLECULAR BIOSCIENCE, 2010, 10 (09) :993-997
[87]   Electrospun Fibers for Dental and Craniofacial Applications [J].
Li, Guo ;
Zhang, Tong ;
Li, Meng ;
Fu, Na ;
Fu, Yao ;
Ba, Kai ;
Deng, Shuwen ;
Jiang, Yan ;
Hu, Jing ;
Peng, Qiang ;
Lin, Yunfeng .
CURRENT STEM CELL RESEARCH & THERAPY, 2014, 9 (03) :187-195
[88]   The fabrication of biomimetic biphasic CAN-PAC hydrogel with a seamless interfacial layer applied in osteochondral defect repair [J].
Liao, Jinfeng ;
Tian, Taoran ;
Shi, Sirong ;
Xie, Xueping ;
Ma, Quanquan ;
Li, Guo ;
Lin, Yunfeng .
BONE RESEARCH, 2017, 5
[89]   Design and development of three-dimensional scaffolds for tissue engineering [J].
Liu, C. ;
Xia, Z. ;
Czernuszka, J. T. .
CHEMICAL ENGINEERING RESEARCH & DESIGN, 2007, 85 (A7) :1051-1064
[90]   Less harmful acidic degradation of poly(lactic-co-glycolic acid) bone tissue engineering scaffolds through titania nanoparticle addition [J].
Liu, Huinan ;
Slamovich, Elliott B. ;
Webster, Thomas J. .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2006, 1 (04) :541-545
45678910111213