Different approaches to synthesising cerium oxide nanoparticles and their corresponding physical characteristics, and ROS scavenging and anti-inflammatory capabilities

被引:53
作者
Wu, Yuao [1 ]
Ta, Hang T. [1 ,2 ,3 ]
机构
[1] Griffith Univ, Queensland Micro & Nanotechnol, Nathan, Qld 4111, Australia
[2] Griffith Univ, Sch Environm & Sci, Nathan, Qld 4111, Australia
[3] Univ Queensland, Australian Inst Bioengn & Nanotechnol, St Lucia, Qld 4072, Australia
基金
英国医学研究理事会;
关键词
OXIDATIVE STRESS; GREEN SYNTHESIS; CYTOTOXICITY; NANOMATERIALS; INFLAMMATION; MITIGATION; MORTALITY; TOXICITY; CELLS; SHAPE;
D O I
10.1039/d1tb01091c
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
The biological applications of cerium oxide nanoparticles (nanoceria) have received extensive attention in recent decades. The coexistence of trivalent cerium and tetravalent cerium on the surface of nanoceria allows the scavenging of reactive oxygen species (ROS). The regeneratable changes between Ce3+ and Ce4+ make nanoceria a suitable therapeutic agent for treating ROS-related diseases and inflammatory diseases. The size, morphology and Ce3+/Ce4+ state of cerium oxide nanoparticles are affected by the synthesis method. This review focuses on various synthesis methods of cerium oxide nanoparticles and discusses their corresponding physical characteristics, and anti-ROS and anti-inflammatory properties.
引用
收藏
页码:7291 / 7301
页数:12
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