Surface Plasmon Resonance-Based Fiber-Optic Metallic Multilayer Biosensors

被引:13
作者
Radha, Sudheer Vasudevan Pillai [1 ]
Nair, Sarath Kumar Santhakumari Amma Ravindran [2 ]
Iyer, Sankararaman Sankaranarayana [1 ]
机构
[1] Univ Kerala, Dept Optoelect, Thiruvananthapuram 695581, Kerala, India
[2] Univ Kerala, Dept Nanosci & Nanotechnol, Thiruvananthapuram 695581, Kerala, India
来源
ACS OMEGA | 2021年 / 6卷 / 23期
关键词
SENSORS; AU; AG; CU;
D O I
10.1021/acsomega.1c01236
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Accurate and quick sensing of various biomolecules relevant to different health conditions is indispensable in modern diagnosis and treatment procedures. Different multilayer metallic surface plasmon resonance (SPR) biosensor configurations comprising Au, Ag, Al, and Cu are analyzed in this work by employing an N-layer matrix formalism as applied to the fixed-angle spectral SPR sensing methodology. Stringent standards for sensitivity, detection accuracy, and figure of merit (FOM) of the sensor configurations are set to analyze the relative merits of one configuration over another. It is observed that three- and four-layer configurations using Al and Cu provide the best FOM among all sensors that passed the set standard criteria. The highest FOM (1433.82/MU) is observed for the four -layer Al/Cu/Al/ Cu sensor for an analyte refractive index of 1.408. The sensors are best suited for detecting analytes with a refractive index range of 1.350-1.414.
引用
收藏
页码:15068 / 15077
页数:10
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