Participation of humoral factors in the regulation of hemopoiesis in cytostatic myelodepression

被引：0
作者：
Dygai, AM [1 ]
Zhdanov, VV [1 ]
Minakova, MY [1 ]
Gol'dberg, ED [1 ]
机构：
[1] Russian Acad Med Sci, Tomsk Res Ctr, Inst Pharmacol, Tomsk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 124卷 / 08期
关键词：
hemopoietic microenvironment; colony-stimulating activity; erythropoietic activity; cytostatics;
D O I：
10.1007/BF02445085
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Production of hemopoietic factors responsible for colony-stimulating and erythropoietic activities by hemopoietic microenvironment is measured and the serum level of these activities in CBA nice treated with various cytostatics is determined. It is shown that the key role in direct stimulation of suppressed hemopoiesis is played by hemopoietic growth factors produced by adherent and nonadherent cells of hemopoietic microenvironment.
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页码：764 / 767
页数：4
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