Antimicrobial Activity of the Crude Ethanol Extract and Fractions from Eugenia uniflora Leaves Against Pseudomonas aeruginosa

被引：0
|
作者：
Fiuza, Tatiana S. [2 ]
Saboia-Morais, Simone M. T. [2 ]
Paula, Jose R. [1 ]
Tresvenzol, Leonice M. F. [1 ]
Carmo Filho, Jose R. [3 ]
Pimenta, Fabiana C. [4 ]
机构：
[1] Univ Fed Goias, Fac Farm, BR-74001970 Goiania, Go, Brazil
[2] Univ Fed Goias, Inst Ciencias Biol, BR-74001970 Goiania, Go, Brazil
[3] Univ Catolica Goias, BR-74605010 Goiania, Go, Brazil
[4] Univ Fed Goias, Inst Patol Trop, BR-74001970 Goiania, Go, Brazil
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2009年 / 28卷 / 06期
关键词：
Antimicrobial activity; Bacterial resistance; Ethanol extract; RESISTANCE;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This study evaluated the antimicrobial activity of the crude ethanol extract and fractions from Eugenia uniflora L. leaves against Pseudomonas aeruginosa. A total of 72 P. aeruginosa isolated from patients of three hospitals in Goiania and 8 standard strains were selected to test antimicrobial activity. The bacteria susceptibility profile against 15 antimicrobial agents was determined using the disc diffusion method. The minimum inhibitory concentration of the crude ethanol extract and the ethyl acetate, chloroform and hexane fractions was determined. Most of the P. aeruginosa analyzed proved resistant to a number of antimicrobial substances and their sensitivity varied from 81.9% sensitivity to meropenem to 0.0% sensitivity to cefotaxim. All the P. aeruginosa were inhibited by the crude extract and by the ethyl acetate fraction. Only 11.25% of the bacteria analyzed were inhibited by the chloroform fraction (8.75 mg/mL MIC). The hexane fraction presented no activity.
引用
收藏
页码：892 / 898
页数：7
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