Synthesis of heat shock proteins (HSP70) in blood leukocytes as a criterion of the resistance to stress injury

被引：6

作者：

Pshennikova, M. G. ^{[1
]}

Zelenina, O. M. ^{[1
]}

Kruglov, S. V. ^{[1
]}

Pokidyshev, D. A. ^{[1
]}

Shimkovich, M. V. ^{[1
]}

Malyshev, I. Yu. ^{[1
]}

机构：

[1] Russian Acad Med Sci, Inst Gen Pathol & Pathophysiol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 142卷 / 06期

关键词：

August and Wistar rats; emotional stress; blood leukocytes; HSP70; proteins; nitric oxide;

D O I：

10.1007/s10517-006-0444-1

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The resistance of August rats to ulceration of the gastric mucosa induced by acute emotional stress was higher than in Wistar rats. August rats exhibited not only more potent activation of the protective nitric oxide system and mobilization of the immune system, but also increased synthesis of cytoprotective heat shock proteins HSP70 in blood leukocytes under stress conditions. Our results indicate that HSP70 protein synthesis in blood leukocytes during stress reflects organism's resistance to stress and, probably, to other adverse factors.

引用

页码：660 / 662

页数：3

共 12 条

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