The Role of Six1 in the Genesis of Muscle Cell and Skeletal Muscle Development

被引：34
作者：
Wu, Wangjun [1 ,2 ]
Huang, Ruihua [1 ,2 ]
Wu, Qinghua [3 ,4 ]
Li, Pinghua [1 ,2 ]
Chen, Jie [1 ]
Li, Bojiang [1 ]
Liu, Honglin [1 ]
机构：
[1] Nanjing Agr Univ, Dept Anim Genet Breeding & Reprod, Coll Anim Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China
[2] Huaian Acad, Nanjing Agr Univ, Huaian 223001, Jiangsu, Peoples R China
[3] Yangtze Univ, Coll Life Sci, Jinzhou 434023, Hubei, Peoples R China
[4] Univ Hradec Kradec Kralove, Fac Informat & Management, Ctr Basic & Appl Res, Hradec Kralove, Czech Republic
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES | 2014年 / 10卷 / 09期
关键词：
Six1; Muscle; Muscle fiber; Muscle progenitors; Regulatory network; Molecular mechanism; MYOGENIC PRECURSOR CELLS; PROTEINS SINE-OCULIS; C-MET RECEPTOR; 6 FAMILY GENES; EYE DEVELOPMENT; HOMEOBOX GENES; TRANSCRIPTION FACTORS; HOMEODOMAIN-PROTEINS; FIBER-TYPE; MYOTONIC-DYSTROPHY;
D O I：
10.7150/ijbs.9442
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The sine oculis homeobox 1 (Six1) gene encodes an evolutionarily conserved transcription factor. In the past two decades, much research has indicated that Six1 is a powerful regulator participating in skeletal muscle development. In this review, we summarized the discovery and structural characteristics of Six1 gene, and discussed the functional roles and molecular mechanisms of Six1 in myogenesis and in the formation of skeletal muscle fibers. Finally, we proposed areas of future interest for understanding Six1 gene function.
引用
收藏
页码：983 / 989
页数：7
相关论文
共 81 条
  • [1] SPECIFICITY OF MINOR-GROOVE AND MAJOR-GROOVE INTERACTIONS IN A HOMEODOMAIN-DNA COMPLEX
    ADES, SE
    SAUER, RT
    [J]. BIOCHEMISTRY, 1995, 34 (44) : 14601 - 14608
  • [2] EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear
    Ahmed, Mohi
    Xu, Jinshu
    Xu, Pin-Xian
    [J]. DEVELOPMENT, 2012, 139 (11): : 1965 - 1977
  • [3] Dual transcriptional activities of SIX proteins define their roles in normal and ectopic eye development
    Anderson, Abigail M.
    Weasner, Bonnie M.
    Weasner, Brandon P.
    Kumar, Justin P.
    [J]. DEVELOPMENT, 2012, 139 (05): : 991 - 1000
  • [4] A novel genetic hierarchy functions during hypaxial myogenesis:: Pax3 directly activates Myf5 in muscle progenitor cells in the limb
    Bajard, Lola
    Relaix, Frederic
    Lagha, Mounia
    Rocancourt, Didier
    Daubas, Philippe
    Buckingham, Margaret E.
    [J]. GENES & DEVELOPMENT, 2006, 20 (17) : 2450 - 2464
  • [5] Bendall AJ, 1999, DEVELOPMENT, V126, P4965
  • [6] Expression of zebrafish six1 during sensory organ development and myogenesis
    Bessarab, DA
    Chong, SW
    Korzh, V
    [J]. DEVELOPMENTAL DYNAMICS, 2004, 230 (04) : 781 - 786
  • [7] Six1a is required for the onset of fast muscle differentiation in zebrafish
    Bessarab, Dmitri A.
    Chong, Shang-Wei
    Srinivas, Bhylahalli Purushottam
    Korzh, Vladmir
    [J]. DEVELOPMENTAL BIOLOGY, 2008, 323 (02) : 216 - 228
  • [8] ESSENTIAL ROLE FOR THE C-MET RECEPTOR IN THE MIGRATION OF MYOGENIC PRECURSOR CELLS INTO THE LIMB BUD
    BLADT, F
    RIETHMACHER, D
    ISENMANN, S
    AGUZZI, A
    BIRCHMEIER, C
    [J]. NATURE, 1995, 376 (6543) : 768 - 771
  • [9] Cloning of the human SIX1 gene and its assignment to chromosome 14
    Boucher, CA
    Carey, N
    Edwards, YH
    Siciliano, MJ
    Johnson, KJ
    [J]. GENOMICS, 1996, 33 (01) : 140 - 142
  • [10] Bovolenta P, 1996, INT J DEV BIOL S1, p73S
123456789