Mucormycosis: A new threat to Coronavirus disease 2019 with special emphasis on India

被引:10
作者
Ghosh, Deganta [1 ]
Dey, Sagardeep [1 ]
Chakraborty, Himanko [1 ]
Mukherjee, Sneha [1 ]
Halder, Ankita [1 ]
Sarkar, Akash [1 ]
Chakraborty, Pallab [2 ]
Ghosh, Rajdeep [3 ]
Sarkar, Joy [1 ]
机构
[1] Dinabandhu Andrews Coll, Dept Bot, Kolkata 700084, West Bengal, India
[2] Acharya Prafulla Chandra Coll, Dept Bot, New Barrakpur, Kolkata 700131, West Bengal, India
[3] Gen Hosp, GSL Med Coll, Rajahmundry 533296, Andhra Pradesh, India
来源
CLINICAL EPIDEMIOLOGY AND GLOBAL HEALTH | 2022年 / 15卷
关键词
Corticosteroid; COVID-19; Diabetics; Mucormycosis; Rhizopus; RHINOCEREBRAL MUCORMYCOSIS; DIABETIC-KETOACIDOSIS; RHIZOPUS INFECTION; FUNGAL-INFECTIONS; ZYGOMYCOSIS; EPIDEMIOLOGY; GRP78; RECIPIENTS; PROTEIN; LOCALIZATION;
D O I
10.1016/j.cegh.2022.101013
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The main reason for the growth of mucormycosis in people with Coronavirus disease-2019 (COVID-19) is mainly produced by Rhizopus spp. The infective mechanisms and issues recognized in Rhizopus spp. are the cell wall, germination proteins, and enzymes assisted to iron sequestration, CotH protein, and positive regulation of the GRP78 cell receptor. Mucormycosis is mainly caused by the Rhizopus spp. such as R. oryzae, R. microsporus, R. arrhizus, R. homothallicus, etc. that are gifted to numerous host defense mechanisms and attribute to the endothelium via specific receptors, GRP78 simplifying their endocytosis and angio-invasion. Factors such as hyperglycemia, elevated iron concentrations, and ketoacidosis have been shown to contribute to the pathogenesis in the tentative situation. The analytical data of 'black fungus disease' or 'mucormycosis', specify India reported for about 42.3% of published cases, followed by the USA about 16.9%, Iraq, Bangladesh, Iran, Paraguay, and 1 case each from Brazil, Mexico, Italy, UK, China, France, Uruguay, Turkey, and Austria. The COVID-19 infection is maybe a predisposing factor for mucormycosis and is related to a high mortality rate. Early recognition and restriction of hyperglycemia, liposomal amphotericin B, and surgical debridement are the bases in the successful managing of mucormycosis.
引用
收藏
页数:16
相关论文
共 149 条
[1]   Cell iron status influences macrophage polarization [J].
Agoro, Rafiou ;
Taleb, Meriem ;
Quesniaux, Valerie F. J. ;
Mura, Catherine .
PLOS ONE, 2018, 13 (05)
[2]   The double-edged sword of systemic corticosteroid therapy in viral pneumonia: A case report and comparative review of influenza-associated mucormycosis versus COVID-19 associated mucormycosis [J].
Ahmadikia, Kazem ;
Hashemi, Seyed Jamal ;
Khodavaisy, Sadegh ;
Getso, Muhammad Ibrahim ;
Alijani, Neda ;
Badali, Hamid ;
Mirhendi, Hossein ;
Salehi, Mohammadreza ;
Tabari, Azin ;
Mohammadi Ardehali, Mojtaba ;
Kord, Mohammad ;
Roilides, Emmanuel ;
Rezaie, Sassan .
MYCOSES, 2021, 64 (08) :798-808
[3]  
Alekseyev Kirill, 2021, J Med Cases, V12, P85, DOI 10.14740/jmc3637
[4]   GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis [J].
Alqarihi, Abdullah ;
Gebremariam, Teclegiorgis ;
Gu, Yiyou ;
Swidergall, Marc ;
Alkhazraji, Sondus ;
Soliman, Sameh S. M. ;
Bruno, Vincent M. ;
Edwards, John E. Jr Jr ;
Filler, Scott G. ;
Uppuluri, Priya ;
Ibrahim, Ashraf S. .
MBIO, 2020, 11 (03)
[5]   Absidia corymbifera infections in neonates [J].
Amin, SB ;
Ryan, RM ;
Metlay, LA ;
Watson, WJ .
CLINICAL INFECTIOUS DISEASES, 1998, 26 (04) :990-992
[6]   Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species [J].
Andrianaki, Angeliki M. ;
Kyrmizi, Irene ;
Thanopoulou, Kalliopi ;
Baldin, Clara ;
Drakos, Elias ;
Soliman, Sameh S. M. ;
Shetty, Amol C. ;
McCracken, Carrie ;
Akoumianaki, Tonia ;
Stylianou, Kostas ;
Ioannou, Petros ;
Pontikoglou, Charalampos ;
Papadaki, Helen A. ;
Tzardi, Maria ;
Belle, Valerie ;
Ettiene, Emilien ;
Beauvais, Anne ;
Samonis, George ;
Kontoyiannis, Dimitrios P. ;
Andreakos, Evangelos ;
Bruno, Vincent M. ;
Ibrahim, Ashraf S. ;
Chamilos, Georgios .
NATURE COMMUNICATIONS, 2018, 9
[7]   A MECHANISM OF SUSCEPTIBILITY TO MUCORMYCOSIS IN DIABETIC-KETOACIDOSIS - TRANSFERRIN AND IRON AVAILABILITY [J].
ARTIS, WM ;
FOUNTAIN, JA ;
DELCHER, HK ;
JONES, HE .
DIABETES, 1982, 31 (12) :1109-1114
[8]   Thrombotic events following tocilizumab therapy in critically ill COVID-19 patients: a Facade for prognostic markers [J].
Atallah, Bassam ;
El Nekidy, Wasim ;
Mallah, Saad I. ;
Cherfan, Antoine ;
AbdelWareth, Laila ;
Mallat, Jihad ;
Hamed, Fadi .
THROMBOSIS JOURNAL, 2020, 18 (01)
[9]   Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis [J].
Ayelign, Birhanu ;
Negash, Markos ;
Genetu, Meaza ;
Wondmagegn, Tadelo ;
Shibabaw, Tewodros .
JOURNAL OF IMMUNOLOGY RESEARCH, 2019, 2019
[10]   PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis [J].
Baldin, Clara ;
Soliman, Sameh S. M. ;
Jeon, Heewon H. ;
Alkhazraji, Sondus ;
Gebremariam, Teclegiorgis ;
Gu, Yiyou ;
Bruno, Vincent M. ;
Cornely, Oliver A. ;
Leather, Helen L. ;
Sugrue, Michele W. ;
Wingard, John R. ;
Stevens, David A. ;
Edwards, John E., Jr. ;
Ibrahim, Ashraf S. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2018, 56 (10)