Early linear growth retardation and later blood pressure

被引:31
作者
Gaskin, PS [1 ]
Walker, SP
Forrester, TE
Grantham-McGregor, SM
机构
[1] Univ W Indies, Trop Metab Res Unit, Kingston 7, Jamaica
[2] Inst Child Hlth, London, England
基金
英国医学研究理事会;
关键词
stunting; systolic blood pressure; pulse rate;
D O I
10.1038/sj.ejcn.1601057
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Objective: To examine the effects of stunting in early childhood on blood pressure in later childhood. Design: A cohort study. Setting: Kingston, Jamaica. Subjects: Seven to eight year old children, 120 stunted (height for age < -2 s.d. of the NCHS references) and 224 non-stunted (height for age > -1 s.d. of the NCHS references) at age 9-24 months. Methods: Stunted and non-stunted children were identified at age 9-24 months by house to-house survey of poor neighbourhoods in Kingston, Jamaica. Blood pressure and anthropometry were measured at age 7-8 y. Birth weight was obtained from hospital records (73%) or maternal recall. Results: The stunted children remained shorter and thinner than the non-stunted ones. In multiple regression analysis adjusting for size and pulse rate, the stunted children had higher systolic blood pressure (P < 0.05). Birth weight was not a significant predictor of systolic blood pressure. Conclusion: Stunting in early childhood may increase the risk of elevated systolic blood pressure in later life. Sponsorship: Nutricia Research Foundation, The Netherlands and the Commonwealth Caribbean Medical Research Council.
引用
收藏
页码:563 / 567
页数:5
相关论文
共 39 条
[1]  
BARKER DJP, 1989, LANCET, V2, P577
[2]   GROWTH INUTERO, BLOOD-PRESSURE IN CHILDHOOD AND ADULT LIFE, AND MORTALITY FROM CARDIOVASCULAR-DISEASE [J].
BARKER, DJP ;
OSMOND, C ;
GOLDING, J ;
KUH, D ;
WADSWORTH, MEJ .
BRITISH MEDICAL JOURNAL, 1989, 298 (6673) :564-567
[3]   RELATION OF FETAL AND INFANT GROWTH TO PLASMA-FIBRINOGEN AND FACTOR-VII CONCENTRATIONS IN ADULT LIFE [J].
BARKER, DJP ;
MEADE, TW ;
FALL, CHD ;
LEE, A ;
OSMOND, C ;
PHIPPS, K ;
STIRLING, Y .
BMJ-BRITISH MEDICAL JOURNAL, 1992, 304 (6820) :148-152
[4]   FETAL AND PLACENTAL SIZE AND RISK OF HYPERTENSION IN ADULT LIFE [J].
BARKER, DJP ;
BULL, AR ;
OSMOND, C ;
SIMMONDS, SJ .
BRITISH MEDICAL JOURNAL, 1990, 301 (6746) :259-262
[5]   The prevalence of hypertension in seven populations of West African origin [J].
Cooper, R ;
Rotimi, C ;
Ataman, S ;
McGee, D ;
Osotimehin, B ;
Kadiri, S ;
Muna, W ;
Kingue, S ;
Fraser, H ;
Forrester, T ;
Bennett, F ;
Wilks, R .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1997, 87 (02) :160-168
[6]  
DEONIS M, 1993, B WORLD HEALTH ORGAN, V71, P703
[7]   BLOOD-PRESSURE IN 1ST 10 YEARS OF LIFE - THE BROMPTON STUDY [J].
DESWIET, M ;
FAYERS, P ;
SHINEBOURNE, EA .
BRITISH MEDICAL JOURNAL, 1992, 304 (6818) :23-26
[8]   EARLY LIFE EXPERIENCE AND ADULT CARDIOVASCULAR-DISEASE - LONGITUDINAL AND CASE-CONTROL STUDIES [J].
ELFORD, J ;
WHINCUP, P ;
SHAPER, AG .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1991, 20 (04) :833-844
[9]   WEIGHT IN INFANCY AND PREVALENCE OF CORONARY HEART-DISEASE IN ADULT LIFE [J].
FALL, CHD ;
VIJAYAKUMAR, M ;
BARKER, DJP ;
OSMOND, C ;
DUGGLEBY, S .
BRITISH MEDICAL JOURNAL, 1995, 310 (6971) :17-19
[10]   Stress response in school-age children who have been growth retarded since early childhood [J].
Fernald, LC ;
Grantham-McGregor, SM .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 68 (03) :691-698