Sedative activity of two flavonol glycosides isolated from the flowers of Albizzia julibrissin Durazz

被引：72

作者：

Kang, TH

Jeong, SJ

Kim, NY

Higuchi, R

Kim, YC ^{[1
]}

机构：

[1] Wonkwang Univ, Coll Pharm, Iksan 570749, South Korea

[2] Kyushu Univ, Fac Pharmaceut Sci, Fukuoka 8128582, Japan

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2000年 / 71卷 / 1-2期

关键词：

Albizzia julibrissin; Leguminosae; flavonoids; sedative activity;

D O I：

10.1016/S0378-8741(99)00202-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The flowers of Albizzia julibrissin are used as a sedative in oriental traditional medicine. The phytochemical study of this plant allowed the isolation of two flavonol glycosides, quercitrin (1) and isoquercitrin (2). The sedative activity of these compounds was evaluated, and both compounds 1 and 2 increased pentobarbital-induced sleeping time in dose-dependent manner in mice. These results support the use of the flowers of this plant as a sedative agent. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：321 / 323

页数：3

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